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Lupus

      3 Big Lupus Themes from EULAR 2024

      Dr. Janet Pope discusses three hot topics in lupus at Eular 2024 in Vienna, Austria
      6 months ago
      3 Big Lupus Themes from EULAR 2024 Dr. Janet Pope discusses three hot topics in lupus at Eular 2024 in Vienna, Austria, including abstracts POS0732 and OP0255. https://t.co/XD1EJW2nNE https://t.co/jALVfebb8t
      Belimumab’s Sustained Impact in Lupus

      SLE a chronic autoimmune multi-system inflammatory condition, can present with
      6 months ago
      Belimumab’s Sustained Impact in Lupus SLE a chronic autoimmune multi-system inflammatory condition, can present with various, sometimes severe, clinical manifestations, leading to high levels of morbidity including impact on quality of life. https://t.co/4Gf5SJN5FG https://t.co/LxCjLQkaYQ
      Glucocorticoids (GC) have been the mainstay of treatment in systemic lupus erythematosus (SLE) for nearly three quarters of a century. Through their genomic and non-genomic actions, GC induce a range…
      Summary of #EULAR2024 #ClinicalPearls

      JAKi have expanding disease data
      ✅ #GCA w #UPA
      ✅ Awaiting data in #SLE w #UPA
      6 months ago
      Summary of #EULAR2024 #ClinicalPearls JAKi have expanding disease data ✅ #GCA w #UPA ✅ Awaiting data in #SLE w #UPA & #Deucravacitinib ✅Use in #JIA ✅No new safety signals @rheumnow @eular_org
      #EULAR2024 POS1325 Childhood onset #lupus is often more severe with high mortality rate. Similar to findings in adults,
      #EULAR2024 POS1325 Childhood onset #lupus is often more severe with high mortality rate. Similar to findings in adults, 2 cSLE patients with refractory disease including failure to CyC, RTX & PLEX responded to CD19 CAR T cells with similar short term safety profile @RheumNow https://t.co/YD2arjxcso
      #EULAR2024 POS0417 Using EXPLORE Inflammation I & II proteomics, marked immune dysregulation was seen in new ANA+ re
      #EULAR2024 POS0417 Using EXPLORE Inflammation I & II proteomics, marked immune dysregulation was seen in new ANA+ referral vs HC. 34% progressed to #lupus & #Sjogren. Six potential baseline biomarkers identified & closely resembled established SLE. Validation is ongoing @RheumNow https://t.co/I6HygqNwf7
      #EULAR2024 LBA0007 More evidence on deep Bcell depletion in #lupus. Open label trial of Daratumumab, anti-CD38 plasma ce
      #EULAR2024 LBA0007 More evidence on deep Bcell depletion in #lupus. Open label trial of Daratumumab, anti-CD38 plasma cell Ab showed rapid reduction in biomarker endpoint, dsDNA, as well as SRI-4 & CLASI-A at Wk12. No SAE but longer F/U needed since IgG reduced by 6g/L @RheumNow https://t.co/IIFPYV9oIr
      Recommendation for management of fatigue in people with rheumatic disease.

      Considering fatigue as a surrogate for infl
      Recommendation for management of fatigue in people with rheumatic disease. Considering fatigue as a surrogate for inflammation and changing medication accordingly is part of it. I will also add yearly blood work including: 1- VitD 2-HBA1c and LDl 3-TsH. https://t.co/3QvPqMxZSN
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