POS0277: proof of concept: Prophlx with canakinumab x 1 dose rather than steroids/colch/NSAIDS when starting pegloticase with MTX in pts with active, refractory gout: 11 pts: #gout flares 0 (compared 54% in MIRROR-C), infusion rxn 0, no safety signal @rheumnow https://t.co/4qFnQTOuq0

• https://twitter.com/KDAO2011/status/1801539126719594706/photo/1

Great 1st #EULAR2024 scientific session: “Asymptomatic” Hyperuricemia — innocent bystander vs. menacing foe. Data re: effects on joints, kidneys, & heart have not supported clear clinical consequences w/ exception of kidney crystal deposition. TIGER Study results eagerly awaited. https://t.co/IPQU3Ww0NA

• https://twitter.com/Tuhina_Neogi/status/1800882316753183034/photo/1
• https://twitter.com/Tuhina_Neogi/status/1800882316753183034/photo/1
• https://twitter.com/Tuhina_Neogi/status/1800882316753183034/photo/1
• https://twitter.com/Tuhina_Neogi/status/1800882316753183034/photo/1

Flavinoids (herbs, cherries, berries) have clinical efficacy in #Gout. Review of the mechanisms of flavonoids in gout includes: - Cox-2 inhibition - Lowers xanthine oxidase activity (mediated thru inflammasome, NOD/TLR4, NFKB, OAT1 & OAT3 transporters https://t.co/UC55GGZBCJ https://t.co/L6nE3BMIj1

• Mechanism of flavonoids in the treatment of gouty arthritis (Review)