Lupus
Pedro Castillo _Castillo_Pedro
3 years 10 months ago
Dr. Petri on COVID19 infection vs vaccination on SLE activity:
💠Infection = NO increase SLE activity
💠Infection =⬇️ cutaneous activity
💠Infection = ⬆️anti-cardiolipin IgG/M
💠Vaccination: no increase in activity NOR aCL IgG/M
https://t.co/fWbotSLS3o
#ACR21 Abst#0858 @RheumNow
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 10 months ago
#ACR21 #Abstr0988 Can we predict who would develop #lupus? Data from the Nurses Health Study showed the best model by combining Genetic Risk Score + Clinical & lifestyle factors (AUC:0.72). Need more diversity as most pts were White and aged 50s @RheumNow https://t.co/4KHiZbRgUK https://t.co/QV4npith9H
The first full day of Abstracts and Presentations from ACR Convergence, was full of highly engaging sessions, quality posters and unique presentations. To hear more about the best of the best, I would encourage you to look at our Day 1 Recap Video and Day 1 ACR Best Abstracts. Here are a few of my favorites from the first day.
Janet Pope Janetbirdope
3 years 10 months ago
How concerned should we be for #hydroxychloroquine retinopathy. >4000 pts prospectively followed. 1/2 w RA & 15% w #SLE. New risks Asian with pericentral pattern and overall. Length of time on use and ⬆️wt based dose per day & CKD all risks. Abst#0989 #ACR21 #ACRBest @RheumNow https://t.co/XTfdQpVC7H
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 10 months ago
#ACR21 #Abstr0865 It’s time for T2T to achieve LLDAS in #lupus. In a study of N=2040 pts, mortality was 2.3% mainly due to infection. Remission off steroid was the best but only met in 14%. LLDAS-50 achieved in 48% pts and ⬇️mortality by 56% @RheumNow https://t.co/CddqMuFIOM https://t.co/g346Cbybep
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 10 months ago
#ACR21 #Abstr0864 How does obesity (BMI=/>30) affect #lupus outcomes? Data from Toronto showed:
💠⬆️hs-CRP
💠No in disease activity over 3yrs
💠⬆️CV events (combination of low grade inflammation + hypertension)
@RheumNow https://t.co/IBu8uNSAJi https://t.co/2aqz5e3rwi
David Liew drdavidliew
3 years 10 months ago
Can patient with low dx activity SLE stop HCQ, or at least try and reduce the dose?
Not if you want to avoid flares.
If there are safer subgroups to try it in, we haven't found them yet
(in fact higher dx activity➡️less risk ?other Rx)
SLICC inception #ACR21 ABST0959 @RheumNow https://t.co/NS2V4dEGHv
TheDaoIndex KDAO2011
3 years 10 months ago
Keep the Hydroxychloroquine!
SLICC cohort eval flare risk in 1460 pts who⬇️or d/c HCQ:
👉pts in remission who d/c HCQ flared HR 2.77 (1.46,5.26)
👉pts in remission who⬇️dose flared HR 2.14 (1.34, 3.42)
Abst#0959 #Plenary #ACR21 @rheumnow #ACRbest https://t.co/92U215s8IP
TheDaoIndex KDAO2011
3 years 10 months ago
Do you order EKGs in everyone starting HCQ? Do you avoid HCQ in patients with heart failure? Will these abstracts impact your practice? Click on link to read more....#ACR21 @rheumnow #HCQ https://t.co/fvUZAvNWa8
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 10 months ago
#ACR21 #Abstr0858 Petri reported effect of #COVID and vaccination in #lupus cohort
💠No increase in activity post-infection
💠⬇️cutaneous activity
💠⬆️ aCL IgG and IgM post-infection,
💠No increase in SLE activity or aCL abs post-vaccination
@RheumNow https://t.co/iAaIfzf33c https://t.co/hA6sk6icrs
Poster Hall