BAFF & APRIL support B cell development, diff, survival.
ALPN-303: Antagonist of both BAFF & APRIL
💠⬇️B cell fxn & Ab production,⬇️Plasma cells
💠⬇️UProt, dsDNA, renal immune complexes (mouse model)
đź’ Pending human studies
https://t.co/kzVpUDuNWs
#ACR21 Abst#1429 @RheumNow
Links:
ALPN-303, an Enhanced, Potent Dual BAFF/APRIL Antagonist Engineered by Directed…
https://bit.ly/3EQDAJk
08-11-2021
