Guselkumab improves anaemia in PsA. Appears to correlate with CRP response, ie inflammatory effect. Anaemia resolution associated good outcomes, but many with good outcomes still anaemic. Abstr#1331 #ACR21 @RheumNow https://t.co/LL63Qc0nk5

Study on enthesitis response to biologic Rx ⭐️TNFI caused a 2❎ 🔽mean ActiveMASEI score compared to secukinumab ⭐️ 🔽PASI and DLQI score more in TNFI than Secukinumab 🔰Superiority of TNFi versus secukinumab in regards to active enthesitis Abst#1356 #ACR21 @Rheumnow https://t.co/wdzMYmn8AJ

Dr Elliott presenting on US assessment of enthesitis with TNFi vs secukinumab. Surprisingly TNFi showed a more marked decrease in US enthesitis. Abstr#1356 #ACR21 @RheumNow https://t.co/XXgYMgkMyP

Guselkumab (IL23p19 inhibitor) positive effect on axial outcomes in PsA, durable response across 2 years. Abstr#1330 #ACR21 @RheumNow https://t.co/8LOSdzCvRc

A meta-analysis of 5 cohort studies showed that PsA is significantly associated with vertebral fractures pooled OR 2.09 (95% CI, 1.11 – 3.96; I2 70%). The review was not suggestive of publication bias @RheumNow #ACR21 Abst#1304 https://t.co/rjC776FXUA https://t.co/QvMWxN6ZZ7

• Increased Risk of Vertebral Fracture Among Patients with Psoriatic Arthritis: A…

Meta-analysis shows increased risk of vertebral fracture in PsA, OR 2.09. Abstr#1304 #ACR21 @RheumNow https://t.co/kTrR7I3HA0

Minimal disease activity achievement in PsA achieved by 22.8% in 6 mo of b/ts DMARD MDA achievers were: ➡️Younger ➡️🔽 Disease duration; ➡️ Male ➡️Non-obese ➡️bDMARD-naïve at baseline ➡️🔼 probability achieving MDA components➕MCID PROMs at 6 mo Abst# 1344 #ACR21 @Rheumnow

Effect of BMI on PRO treatment response in PsA. Increasing BMI associated with lower response. More pronounced in TNFi than IL-17 or JAKi. Abstr#1327 #ACR21 @RheumNow https://t.co/qhgVlW72uM

AS and PsA: Mortality vs Gen Pop (meta-analysis) AS: 👉⬆️All-cause 👉⬆️CVD PsA: 👉All-cause not higher 👉⬆️CVD, Respiratory, and Infectious etiologies Important to consider CVD and other comorbidities. https://t.co/9K4qNpYvMb #ACR21 Abst#0569 @RheumNow

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