New data to guide role of long-term, low dose GC in GPA Active GPA s/p tx -> randomized to d/c pred within 1 mo or stay on 5mg daily Fewer relapses on 5mg pred but w/qualifications: 👉 most flares = minor 👉 no difference in flares if RTX on board @RheumNow #ACR24 Abst 0774 https://t.co/Jvc40QWLqM

• https://x.com/Dr_Brian_MD/status/1857912184010928404/photo/1
• https://x.com/Dr_Brian_MD/status/1857912184010928404/photo/1

Coming from somewhere where biosimilars are SOC for many years, I just find it wild how things are biosimilar wise in the US. Reflected by so many abstracts, including lots of oral presentations, essentially on showing biosimilars work. #ACR24 @RheumNow

Stone et al. Phase 3 RCT B-cell depletion with CD19 targeting agent Inebilizumab in IgG4-RD. HR 0.13 (0.06, 0.28) for flare. @RheumNow #ACR24 Abstr#0775 https://t.co/Kd4Xmoc5e6 https://t.co/Al6gOA1F8K

• A Phase 3, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study of I…
• https://x.com/RichardPAConway/status/1857866477065416868/photo/1

Abstract #0805 Data from OTIS Registry shows Certolizumab pegol (Cimzia) exposure during pregnancy was not associated with increased risk of major birth defects, structural defects, or adverse pregnancy outcomes. #ACR24 @RheumNow

What's the assoc between RA disease activity & ILD? Results @MassGenBrigham show early active RA is assoc with ➡️6x incr risk of #ILD ➡️4x incr risk of RA-related lung disease Early DMARDs are vital to reduce articular & extra-articular manifestations! Ab0802 #ACR24 @RheumNow

❔Can rheum drugs have beneficial effects on cognition? 💊Possible benefits with MTX and TNFis but certainly an active area of research and more studies needed #ACR24 @RheumNow https://t.co/lCnIRLwNjK

• https://x.com/DrMiniDey/status/1857852286778634671/photo/1

Ab#0458 #ACR24 10 year outcomes of 176 patients with seroneg RA 32 pts (18%) had change in dx - SpA (11), seropos RA (6), OA (5), crystal (3), CTD (3), Ifn-related/paraneopl/RS3PE, sarcoid (1) 40 (23%) had drug-free remission 30 (17%) started b/tsDMARD @RheumNow