Not agreement on what to do re tests/referrals for NPSLE. Answers likely vary reflecting the broad spectrum of CNS lupus #EULAR2020 @RheumNow @eular_org @CRASCRRheum https://t.co/iJkgz2iMO9

• https://twitter.com/Janetbirdope/status/1268575483744129027

Hand OA Rx strikes out. HCQ Rx neg and colchicine Trial negative. I wouldn’t put hand OA as same category of no Rx as for SSc and Sjogrens but agree though nuts to crack @eular_org @CRASCRRheum @earlyarthritis #EULAR2020 https://t.co/QRe3UpKpbz

• https://twitter.com/rheumnow/status/1269051282238701569

#EULAR2020 OP0333: Could SLE itself be a risk factor for retinopathy (not just because of HCQ)? @Janetbirdope study of >600 pts noted retinopathy risk factors: 1. longer duration of antimalarials 2. any use of chloroquine 3. SLE (OR 16.1 CI 2.1-125) @RheumNow https://t.co/seAR42K1SU

#EULAR2020 THU0260 LESS IS BEST when it comes to steroids: Singapore 10 yr retrospect SLE study noted GCs dose is an independent predictor of mortality for hospitalized infection even when adjusted for disease activity.

#tacrolimus #prograf is non inferior to #MMF #cellcept in #lupus #nephritis induction. We’ve been doing it for years but great to see some solid RCT data behind this. #rheumatology #SLE #autoimmune https://t.co/CblD4GaXCp

• https://twitter.com/ard_bmj/status/1265674753781751813

Updated #EULAR2020 guidelines on management of #lupus #nephritis #SLE #rheumatology #autoimmune #SLE https://t.co/zk2QXXRvTy

#EULAR2020 THU0268 Neuro-develp't in 60 children w/ SLE +APS mothers (n=38): 25% ADHD 93% recent memory delay (assc w/⬆️tetrahydrobiopterin level. p=0.01) 40% speech delay 39.4% maternal APS assc w/special needs education in offsprings age >2 yrs, p<0.05 @rheumnow

#EULAR2020 Dr. V Ritschl:EULAR Task Force on Patient Adherance: 30-80% of pts do not adhere to Rx. resulting in ⬆️dz severity, pain, fatigue, depression, decreased in function, physical activity. HCPs should discuss adherance reg. & explore factors affecting adherance. @RheumNow

ENbrel works in long term for the few people left on the drug at 10 yrs with SpA. Enormous dropout. If you are still on Rx for a decade you are in the minority. Drop out of TNFi in SpA mirrors RA & PsA @RheumNow @eular_org @CRASCRRheum @earlyarthritis #EULAR2020 https://t.co/dLS2fw5uRP

• https://twitter.com/uptotate/status/1269358046150643713

#EULAR2020 THU0225 Results of a Retrospect UK study: Monitor SLE patients with Sm+Ro+RNP autoAb combo closely; these patients have a higher rate (90.6%) of developing LN within 5 years of diagnosis compared to those w/o Ab (55.8%), p=0.002. @RheumNow

Can you classify SLE by labs only but should you? Serology is part of criteria but why dx with only +ANA, +antiDNA and no other CTD characteristics. Would need cytopenias & RBC casts to think of lab dx of SLE OP0094 @LupusCanada @RheumNow @eular_org #EULAR2020 @CRASCRRheum https://t.co/Jr6SRr3HR1

• https://twitter.com/kdao2011/status/1269048405210337280

Avacopan is as effective as steroids in ANCA Assoc Vasculitis – 330 pt RCT AAV Rx w/ RTX or CTX but randomized to prednisone or avacopan (C5aR antagonist). Avacopan=prednisone remission rates same (72% vs 70%) wk 26 & wk 52 (66% vs 55%). #EULAR2020 #OP0011 https://t.co/WIXJCYkxSb

• https://bit.ly/2Y3zV7g

#EULAR2020 OP0096 Dr. L Chatzis study on Sjogren: 1. 2nd most common autoimm dz in women 2. women:men ratio 20:1 (not 9:1) 3. 2 types Ro-Ab: nuc. Ro60 (assc w/La)and cytopls. Ro52 (assc w/ILD/myositis) 4. Seroneg. Sjogren's (neg Ro/La/RF) good prognosis:⬇️lymphoma @RheumNow https://t.co/fV3ltQqnkf

NPSLE is more than a headache! probs with dx, uncertain Rx, overlap with common probs - infection, pain, fibromyalgia, drug side effects, etc. Spectrum in NPSLE just like SLE has a spectrum of cutaneous findings T Huizanga discusses @eular_org #EULAR2020 @RheumNow @CRASCRRheum https://t.co/sdw0xavWBq