Lupus
In this week's podcast, Drs. Artie Kavanaugh and Jack Cush present highlights from the virtual EULAR2020 meeting held June 3-6, 2020. Featured reports include the SELECT-CHOICE study, the EXCEED trial, Avacopan in AAV, BeST mortality outcomes, BLISS-LN study, biosimilars and tofa in systemic sclerosis.
Autoinflammatory/Still's Disease Panel - EULAR2020
Drs. Olga Petryna, Petros Efthimiou, Apostolos Kontzias and Jack Cush discuss autoinflammatory highlights from the Virtual EULAR 2020 meeting June 3-6
These were my top abstracts from Thursday, 4th of June at EULAR 2020:
These were my top abstracts from Thursday, 4th of June at EULAR 2020:
For a disease that has been recognized since the days of Hippocrates, we are finally making some progress towards understanding systemic lupus erythematosus (SLE) and how to tame the wolf. Listed below are the top 5 studies and their summaries presented at the recent EULAR e-Congress conference streamed from Germany that I found impactful:
Flares in ANCA-associated vasculitis are difficult to predict, but serum calprotectin may help predict relapse and renal failure, according to data presented at the EULAR 2020 virtual meeting this week.
These were my top abstracts from Thursday, 4th of June at EULAR 2020.
GCA and Risk of Cancer or Visual Loss
Dr. Olga Petryna from EULAR2020 Virtual Conference
OP0149 Tocilizumab Treats Visual Loss in GCA
OP0143 GCA in Israel and risk of Cancer
Enticing New Options in ANCA-Associated Vasculitis
Dr. David Liew from EULAR2020 ANCA-Associated Vasculitis Avacopan vs Prednisone MAINRITSAN 2 study - Calprotectin
Olga Petryna DrPetryna
5 years ago
#EULAR2020 #op0201 nationwide cohort study: higher incidence of dementia in SLE (3.9/1000pys) vs non-SLE ( 2.73/1000pys). HR 1.43. In SLE risk of Alzheimer’s 1.4x &risk of vascular dementia 1.6x Higher than non-SLE cohort. Further studies to identify mechanism needed @RheumNow
Olga Petryna DrPetryna
5 years ago
#EULAR2020 #op0028 12 wk ph3 RELIEF study: Apremilast effectively relieves OU pain and OU number after 12 wks of 30 mg bid Rx. Great proportion of APR PTs achieved >10 mm &>30 mm improvement in OU pain @RheumNow https://t.co/p71sz9XL0e
David Liew drdavidliew
5 years ago
Here's the data for GCA (even though labelled PMR) using the same methods, both looking at first 1y.
Here's what gets me - it's obviously worse, but not that much worse... everyone's looking for steroid-sparing agents in GCA, but PMR's left behind?
OP0275 #EULAR2020 @RheumNow https://t.co/YWkNBVitGa
David Liew drdavidliew
5 years ago
Behcet's ulcers can be a real pain.
I've heard pentoxifylline gel be discussed before, here's some early data to back it up (need bigger trial).
Tastes terrible, though - so maybe this?
https://t.co/TrSlIKdWX3
(or a commercial prep might solve it)
SAT0260 #EULAR2020 @RheumNow https://t.co/lvDY39ZbIH
Janet Pope Janetbirdope
5 years ago
Whom with GCA should receive tocilizumab? What happens when it is stopped? Optimal dose for maintenance weekly or Q2 weekly? GiACTA gives only some answers. Need RWE #EULAR2020 @eular_org @RheumNow @CRASCRRheum @earlyarthritis #vasculitis https://t.co/aNvR14vfEV
Poster Hall