TNF inhibitor
In this week's podcast, Drs. Artie Kavanaugh and Jack Cush present highlights from the virtual EULAR2020 meeting held June 3-6, 2020. Featured reports include the SELECT-CHOICE study, the EXCEED trial, Avacopan in AAV, BeST mortality outcomes, BLISS-LN study, biosimilars and tofa in systemic sclerosis.
These were my top abstracts from Thursday, 4th of June at EULAR 2020:
These were my top abstracts from Thursday, 4th of June at EULAR 2020:
Updated EULAR Recommendations for RA Management
Dr. Kathryn Dao from EULAR2020 Virtual Conference
Imaging and Remission Axial Spondyloarthritis
Dr. Olga Petryna from EULAR2020 Virtual Conference
OP0079 - what MRI findings are most predictive in AxSpa
OP0314 - Drug free remission in AxSpA
Biosimilars in Spondyloarthritis
Dr. Rachel Tate from EULAR2020 Virtual Conference 0632
- ETN Biosimilar in Reactive Arthritis 0650
- Treasure Study in infliximab biosimilar in SpA
David Liew drdavidliew
5 years ago
Lots of talk about best bDMARDs in RA-ILD, but what about in RA-assoc bronchiectasis?
@Yuz6Yusof found rituximab had better 'lung survival' vs TNFi (similar baseline stats)
Something to consider in these difficult-to-treat pts?
@LeedsBRC Newcastle THU0143 #EULAR2020 @RheumNow https://t.co/XpffkDNqhU
k dao KDAO2011
5 years ago
#EULAR2020 Dr. V Ritschl:EULAR Task Force on Patient Adherance: 30-80% of pts do not adhere to Rx. resulting in ⬆️dz severity, pain, fatigue, depression, decreased in function, physical activity. HCPs should discuss adherance reg. & explore factors affecting adherance. @RheumNow
Janet Pope Janetbirdope
5 years ago
ENbrel works in long term for the few people left on the drug at 10 yrs with SpA. Enormous dropout. If you are still on Rx for a decade you are in the minority. Drop out of TNFi in SpA mirrors RA & PsA @RheumNow @eular_org @CRASCRRheum @earlyarthritis #EULAR2020 https://t.co/dLS2fw5uRP
Dr. Rachel Tate uptoTate
5 years ago
Study in Norway reveals that the majority of the women w/ SpA were not treated with TNF inhibitors before or during pregnancy. Few on TNFi were continued on tx during pregnancy. #EULAR2020 @RheumNow https://t.co/t7B6pASeWQ https://t.co/BwU6RF5Qkn
Dr. Rachel Tate uptoTate
5 years ago
Switching TNFi to VDZ in pts IBD-related SpA associated w/ articular exacerbation of SpA in 1 out of 4 patients within the first 5 months. New-onset MEM is also observed in up to 15% of patients with IBD treated with VDZ. #EULAR2020 @RheumNow https://t.co/ZVjZC7hvxs https://t.co/d1RT3GzB2b
k dao KDAO2011
5 years ago
#EULAR2020 Recc for irAEs w/ICI:
1. GC's ok, goal<10 mg/d, any csDMARD, bDMARD (TNFi/IL-6),🚫ABT xcept life-threatening myositis
2. Myositis beware bulbar signs: dysphagia, dysarthria, dysphonia: stop ICIs,⬆️GC, IVIG/PE
3. Don't test autoAbs b/f ICI Rx
https://t.co/P5jDgnjK94
Janet Pope Janetbirdope
5 years ago
Don’t forget significant fibrosis with ILD has +RCT with nintedanib INBUILD study. Lots of buzz of RA ILD where MTX is OK, TNFi may have more ILD than other bDMARDs, biomatkers KL-6 @eular_org OP0038 #EULAR2020 @CRASCRRheum https://t.co/OihF3LmNYQ
Poster Hall