Study of the French registries for TCZ, RTX, ABA, compared the risk of GI perforations (GIP). GIP risk was higher with TCZ (vs RTX,ABA) but was largely due to TCZ increasing the risk of diverticulitis. #EULAR2020 #OP0022 https://t.co/MGGWiVh5Jv https://t.co/nC2NblYnGO

• https://bit.ly/2XC5gyX

When starting IV Pegloticase in #Gout, Do you start a DMARD too? #EULAR2020

#EULAR2020 Recc for irAEs w/ICI: 1. GC's ok, goal<10 mg/d, any csDMARD, bDMARD (TNFi/IL-6),🚫ABT xcept life-threatening myositis 2. Myositis beware bulbar signs: dysphagia, dysarthria, dysphonia: stop ICIs,⬆️GC, IVIG/PE 3. Don't test autoAbs b/f ICI Rx https://t.co/P5jDgnjK94

• https://ard.bmj.com/content/early/2020/04/23/annrheumdis-2020-217139

Can you classify SLE by labs only but should you? Serology is part of criteria but why dx with only +ANA, +antiDNA and no other CTD characteristics. Would need cytopenias & RBC casts to think of lab dx of SLE OP0094 @LupusCanada @RheumNow @eular_org #EULAR2020 @CRASCRRheum https://t.co/Jr6SRr3HR1

• https://twitter.com/kdao2011/status/1269048405210337280

Avacopan is as effective as steroids in ANCA Assoc Vasculitis – 330 pt RCT AAV Rx w/ RTX or CTX but randomized to prednisone or avacopan (C5aR antagonist). Avacopan=prednisone remission rates same (72% vs 70%) wk 26 & wk 52 (66% vs 55%). #EULAR2020 #OP0011 https://t.co/WIXJCYkxSb

• https://bit.ly/2Y3zV7g

OU=Oral Ulcers https://t.co/1LPye7ohM1

• https://twitter.com/DrPetryna/status/1269291495871385601

Do not be tempted to stop MTX or other DMARDs perioperatively! They probably help rather than harm #EULAR2020 https://t.co/jb4ZuZlqSu

RA pt not responding to a 1st biologic; what you predict in a Head to Head - Abatacept vs Upadacitinib?

#EULAR2020 #op0225 sub study of OPAL Balance: withdrawal of MTxdoes not negatively impact Tofa efficacy in PsA. At 6 mo deltaPASDAS 0.229 (0.079) for tofa mono & 0.q138 (0.081) for tofa+mtx. LFT elevation more common in combination arm @RheumNow https://t.co/NO1agViScD

#EULAR2020 #fri0505 Still’s pts who are able to achieve remissions w/longer itnervals btw tocilizumab infusions & lower dose of prednisone more likely to successfully withdraw Toci. Time to symptom recurrence in relapse group 7.8 mo. Older pts more likely to relapse @RheumNow

Main factors influencing #physicalactivity in inflammatory #arthritis patients are psychological ➡️Main factor related to knowledge of benefits of #exercise & symptoms ➡️Modifiable ➡️Health professional support key FRI0642-HPR #EULAR2020 👉🏽https://t.co/Vdc7rjnC6Y by @DavergneT https://t.co/aMUHA5IMrn

• https://ard.bmj.com/content/79/Suppl_1/921.1

@Janetbirdope @eular_org @RheumNow @CRASCRRheum @earlyarthritis Good question. I suspect it may be a class effect but would be good to see H2H btw JAKs one day. If selective JAK 1 inhibition provides more, less or same efficacy is still not clear to me

Don’t forget significant fibrosis with ILD has +RCT with nintedanib INBUILD study. Lots of buzz of RA ILD where MTX is OK, TNFi may have more ILD than other bDMARDs, biomatkers KL-6 @eular_org OP0038 #EULAR2020 @CRASCRRheum https://t.co/OihF3LmNYQ

#EULAR2020 OP0096 Dr. L Chatzis study on Sjogren: 1. 2nd most common autoimm dz in women 2. women:men ratio 20:1 (not 9:1) 3. 2 types Ro-Ab: nuc. Ro60 (assc w/La)and cytopls. Ro52 (assc w/ILD/myositis) 4. Seroneg. Sjogren's (neg Ro/La/RF) good prognosis:⬇️lymphoma @RheumNow https://t.co/fV3ltQqnkf

NPSLE is more than a headache! probs with dx, uncertain Rx, overlap with common probs - infection, pain, fibromyalgia, drug side effects, etc. Spectrum in NPSLE just like SLE has a spectrum of cutaneous findings T Huizanga discusses @eular_org #EULAR2020 @RheumNow @CRASCRRheum https://t.co/sdw0xavWBq