RA pt not responding to a 1st biologic; what you predict in a Head to Head - Abatacept vs Upadacitinib?

#EULAR2020 #op0225 sub study of OPAL Balance: withdrawal of MTxdoes not negatively impact Tofa efficacy in PsA. At 6 mo deltaPASDAS 0.229 (0.079) for tofa mono & 0.q138 (0.081) for tofa+mtx. LFT elevation more common in combination arm @RheumNow https://t.co/NO1agViScD

#EULAR2020 #fri0505 Still’s pts who are able to achieve remissions w/longer itnervals btw tocilizumab infusions & lower dose of prednisone more likely to successfully withdraw Toci. Time to symptom recurrence in relapse group 7.8 mo. Older pts more likely to relapse @RheumNow

OU=Oral Ulcers https://t.co/1LPye7ohM1

• https://twitter.com/DrPetryna/status/1269291495871385601

Main factors influencing #physicalactivity in inflammatory #arthritis patients are psychological ➡️Main factor related to knowledge of benefits of #exercise & symptoms ➡️Modifiable ➡️Health professional support key FRI0642-HPR #EULAR2020 👉🏽https://t.co/Vdc7rjnC6Y by @DavergneT https://t.co/aMUHA5IMrn

• https://ard.bmj.com/content/79/Suppl_1/921.1

@Janetbirdope @eular_org @RheumNow @CRASCRRheum @earlyarthritis Good question. I suspect it may be a class effect but would be good to see H2H btw JAKs one day. If selective JAK 1 inhibition provides more, less or same efficacy is still not clear to me

Don’t forget significant fibrosis with ILD has +RCT with nintedanib INBUILD study. Lots of buzz of RA ILD where MTX is OK, TNFi may have more ILD than other bDMARDs, biomatkers KL-6 @eular_org OP0038 #EULAR2020 @CRASCRRheum https://t.co/OihF3LmNYQ

#EULAR2020 OP0096 Dr. L Chatzis study on Sjogren: 1. 2nd most common autoimm dz in women 2. women:men ratio 20:1 (not 9:1) 3. 2 types Ro-Ab: nuc. Ro60 (assc w/La)and cytopls. Ro52 (assc w/ILD/myositis) 4. Seroneg. Sjogren's (neg Ro/La/RF) good prognosis:⬇️lymphoma @RheumNow https://t.co/fV3ltQqnkf

NPSLE is more than a headache! probs with dx, uncertain Rx, overlap with common probs - infection, pain, fibromyalgia, drug side effects, etc. Spectrum in NPSLE just like SLE has a spectrum of cutaneous findings T Huizanga discusses @eular_org #EULAR2020 @RheumNow @CRASCRRheum https://t.co/sdw0xavWBq

Dan Clauw: obese patients with chronic pain reported improved pain levels very early with low calorie diet, long before weight loss, suggesting the diet may be having a more direct effect. https://t.co/aZDOtBd9mz

• https://twitter.com/azbib/status/1268913456738177024

Majority are correct. 1/3 of SAPHO meet PsA criteria esp if no osteitis @RheumNow @eular_org @CRASCRRheum @earlyarthritis #EULAR2020 https://t.co/B9wp8JxWpI

• https://twitter.com/janetbirdope/status/1268262664385462272

What % of SAPHO pts do you think have PsA? More if synovitis Less if osteitis #EULAR2020 @eular_org @RheumNow @CRASCRRheum AB0038

When making a dx of neuropsychiatric SLE I order labs AND @RheumNow @eular_org @CRASCRRheum @earlyarthritis #EULAR2020

#Upadacitinib #psoriaticarthritis Upa works in PsA including imaging and when they show it surprising good PASI scores as well https://t.co/ZWqj8ythHB

#guselkumab #axialdisease - who would have thunk it - IL23 p19 works in axial involvement PsA with radiology! https://t.co/TaSFBJFRnx