Can you ⬇️ #Glucocorticoids or #immunesuppressive in #SLE & change am’t of damage From Asia Pacific #lupus collab (Biologics not included) Compared 7.5 mg #prednisone or less Or DMARD 1/2 flared after LLDAS ⬇️dose didn’t prevent damage #EULAR2024 @eular_org @RheumNow https://t.co/QmjEz87Cvw

• https://twitter.com/Janetbirdope/status/1801192968524538095/photo/1

#EULAR2024 Cutaneous #lupus is variable & can be difficult to treat. Promising post-hoc data frm Phase 2 RCT showing Deucravacitinib (Tyk2-i) led to improvement & sustained CLASI-50 response in all subtypes (ACLE, SCLE, Chonic and Discoid) @RheumNow #EULARBEST https://t.co/ArAzdLYiYY

• https://twitter.com/Yuz6Yusof/status/1801129647603658984/photo/1
• https://twitter.com/Yuz6Yusof/status/1801129647603658984/photo/1

#EULAR2024 OP0043 Data from UK BILAG-BR registry showed in n>100 patients w neuropsychiatric #lupus (NPSLE), over 2/3 improved with rituximab. NPSLE tended to occur with other #SLE features and with high level of organ damage @RheumNow https://t.co/q5olZgr6Pt

• https://twitter.com/Yuz6Yusof/status/1801123910437482766/photo/1

#EULAR2024 OP0077 How can we improve Bcell killing and does deep depletion matter? Biomarkers from RCT showed Obinutuzumab led to profound circulatory depletion in #lupus nephritis & those w sustained depletion had better complete renal response than those who didn’t @RheumNow https://t.co/2KTZBR2njk

• https://twitter.com/Yuz6Yusof/status/1801116419540586582/photo/1

Who needs intensive therapy in #lupus Intensive Rx in #SLE from 2 inception cohorts in Leeds Either #Cyclo or #biologics ⬆️ If low complement Within 2 yrs after #dx #SLEDAI >9 AntiRo+ OP0187 #EULAR2024 @RheumNow @eular_org https://t.co/oKhwMmHhSs

• https://twitter.com/Janetbirdope/status/1801190154675085384/photo/1
• https://twitter.com/Janetbirdope/status/1801190154675085384/photo/1

3 facts in #lupus to make you think 🤔 💧biomarkers in #SLE blood & #urine May predict #activity OP0255 #Membranous #nephritis is serious in SLE @ZahiTouma POS0732 #prednisone dose irrelevant for #damage if in LLDAS -no diff between 7.5mg vs 5mg OP0124 #EULAR2024 @RheumNow

#Hope for patients with #active #SLE The next hurdle is getting through ▶️Phase3 #RCTs And ▶️Obtaining drug reimbursement so patients can get access to effective #lupus #Rx #EULAR2024 @RheumNow @eular_org https://t.co/sGzQXO4A2r

• https://twitter.com/lupusreference/status/1800914620653420937