Psoriatic arthritis

2 years 11 months ago
Dermatologists doing ultrasound (US) for earlier diagnosis of PsA? Grobelski et al showed in this study of 140 PsA patients, pre-US sensitivity/specifity was 81%/55%, post-US this changed to 62%/91%. Targeted US improved accuracy of referrals for PsA #EULAR2022 @RheumNow OP0029 https://t.co/iajqMuPqcd


2 years 11 months ago
Kading et al reports axial disease in 1/3 of patients with PsA, 55% females, 45% HLA-B27+, in 20% there was spinal but no SI joint involvement. Starts to define the Axial PsA patient as more female, less HLA-B27+ and may have only spinal inflammation #EULAR2022 @RheumNow OP0026
Are Tyk2 inhibitors JAK inhibitors?
Yes, no, maybe
Answer
Tyrosine kinase 2 (TYK2) is a member of the JAK kinase family. These molecules regulate signal transduction downstream of receptors for…

2 years 11 months ago
Important to capture MDA in the first year! Failure to achieve MDA in 1st year after PsA diagnosis associated with worse quality of life persisting despite intensified treatment.
@RheumNow #EULAR2022 ABST#OP0028 https://t.co/FrO569J10S


2 years 11 months ago
No longer a "seronegative" disease?
Serological collagen biomarkers (degradation markers of type I and VI collagen) can differentiate PsO pts from PsA.
Potential biomarkers of MSK involvement?
@RheumNow #EULAR2022 ABST#OP0031 https://t.co/vS6mD5PUxw


2 years 11 months ago
6 psoriatic disease specific risk factors associated with incident cardiovascular events in PsA/PsO patients: PsO area, TJC, SJC, HAQ score, ESR, daily use of NSAIDs
@RheumNow #EULAR2022 #ABSTOP0030
At EULAR 2022, I look forward to key topics and presentations in psoriatic arthritis (PsA). I will be sharing the details of these studies once they are presented.
There are new therapies that…

2 years 11 months ago
Do biomarkers correlate with change in disease activity in #PsA? Esp IL17F not so much other IL17s, and IL6, IL23. Ian McInnes ? next steps 🤷♀️ to separate responder and non responder @RheumNow #EULAR2022 OP0024 https://t.co/JMmENRa80t


2 years 11 months ago
Proton Rahman discusses #PsA and #fatigue ⬇️ in #Guselkumab RCTs. 2/3 of fatigue was explained by pt factors - pt global and pain, skin, joints, CRP, function drove the data. Ask pt and treat what is treatable.
#OP0025 @eular @RheumNow https://t.co/x4T6sPEi8o
