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Fibromyalgia/Pain

      The big news this week: the approval of deucravacitinib (a new class of drug?) for psoriasis; the 2022 ACR guidance on glucocorticoid-induced osteoporosis; a national poll of older adults over the age of 50 who claimed self-reported or doctor-diagnosed arthritis; and much more. Let's review these and other news, journal reports and announcements from this past week.
      2022 Univ of Michigan Natl Poll on Healthy Aging finds that 70% of older adults reported joint pain (more in Women 75% v

      Dr. John Cush RheumNow

      2 years 9 months ago
      2022 Univ of Michigan Natl Poll on Healthy Aging finds that 70% of older adults reported joint pain (more in Women 75% vs 65%M). 30% have a HCP dx of #OA, 8% RA, 7% gout or pseudogout & 5% w/ another kind of arthritis https://t.co/yno8RgCRQS https://t.co/yTMLHsbGOU
      Dr. Beth Wallace and colleagues at the University of Michigan surveyed a national sample of older adults (50–80 yrs) and found that 70% currently report experiencing joint pain and 60% reported being told by a health care professional that they have arthritis. 
      Rheums! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast.

      Dr. John Cush RheumNow

      2 years 9 months ago
      Rheums! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/1aSrRsLkel https://t.co/gmh155ty6w
      B12 or Placebo effect? Open label study of B12 (1000mcg/d) in 29 fibromyalgia pts showed after 50d, significant reductio

      Dr. John Cush RheumNow

      2 years 9 months ago
      B12 or Placebo effect? Open label study of B12 (1000mcg/d) in 29 fibromyalgia pts showed after 50d, significant reductions in FM Impact Quest. (FIQR; 49.8 to 40.00; p< 0.01), Function, Sxs, anxiety scores all signif improved. https://t.co/MtJWy5xlz9 https://t.co/kzvA1wd3zb
      Longitudinal study of 411 adult fibromyalgia pts showed that 73.2% had depression at enrollment. Higher depression score

      Dr. John Cush RheumNow

      2 years 9 months ago
      Longitudinal study of 411 adult fibromyalgia pts showed that 73.2% had depression at enrollment. Higher depression scores at baseline predicted poorer functional outcomes. Effectively treated depression resulted in improved functioning at follow-up. https://t.co/D43r4Z5llU https://t.co/a9EgyJLHza
      Goofy But True
      Dr. Jack Cush discusses declining survival rates in the USA, FDA approvals of new COVID subvariant boosters and other odd and possibly true new research reports from the past week on RheumNow.com.
      While hypertension and arthritis are very common disorders, the association between them is unclear.  Analysis of NHANES data suggests that both rheumatoid arthritis (RA) and osteoarthritis (OA) are strongly associated with hypertension (HTN). The NHANES (National Health and Nutrition Examination Survey) of non-pregnant adult, aged ≥ 20 years examined data 48,372 eligible participants between 1999–2018.
      Study of 497 pts referred by general practitioners to rheumatologist (2018-19) showed:
      - GP Dx changed by Rheum in 58%

      Dr. John Cush RheumNow

      2 years 9 months ago
      Study of 497 pts referred by general practitioners to rheumatologist (2018-19) showed: - GP Dx changed by Rheum in 58% - Low complexity Dx (FM, OA) acct for 50% referrals - 46% of referrals inappropriate - GP correlations w/ Rheum Dx poor (κ < 0.5) https://t.co/q592iHQZbq https://t.co/XyPdtpHQGK
      OPTION-DM study of 140 diabetic neuropathy pts Rx for 16 weeks w/ one agent (&amp; if no response) an add-on agent. At

      Dr. John Cush RheumNow

      2 years 9 months ago
      OPTION-DM study of 140 diabetic neuropathy pts Rx for 16 weeks w/ one agent (& if no response) an add-on agent. At wk 16, all 3 regimens lowered nerve pain score from 6.6 to 3.3 w/ no difference between Elavil+Lyrica, Lyrica+Elavil, o Cymbalta+Lyrica) https://t.co/rijJyq1DYL https://t.co/NwHF6xuF0j
      RT @Lupusreference: ✅ Probably one of my most important slides ⬇️
      WHY IS MY #TREATMENT NOT WORKING (or not working

      Laurent ARNAUD Lupusreference

      2 years 9 months ago
      ✅ Probably one of my most important slides ⬇️ WHY IS MY #TREATMENT NOT WORKING (or not working enough) 😭 This is really a question we're dealing with everyday in #rheumatology when taking care of patients with #autoimmune and other rheumatic diseases 👍 https://t.co/osUPYSvuWf
      Data from Data FORWARD (The National Databank for Rheumatic Diseases) reveals that nearly two-thirds of rheumatoid arthritis (RA) patients have self-reported sleep problems. The FORWARD study, a registry that includes over 4200 RA patients), collects data on obstructive sleep apnea (OSA), restless legs syndrome (RLS), and short sleep (SS) problems. SS was based on self-reported average sleep time (<6 hours). 
      In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo. BMJ has published a metanalysis of the efficacy and safety of viscosupplementation (intraarticular hyaluronic acid injection) in knee osteoarthritis patients. This is one of many such reviews, all ending with the same conclusion.
      The NY Times reports that a recent survey of drug use indicates that daily consumption of marijuana among young adults nearly doubled in the last decade. This is coupled with growing mainstream acceptance of cannabis and hallucinogenic compounds.
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