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Autoinflammatory

      In comments submitted to the Centers for Medicare and Medicaid Services (CMS) in response to the CY 2023 Medicare Physician Fee Schedule and Quality Payment Program proposed rule, the American College of Rheumatology applauded proposals that would provide more flexibility and improve care coordination, while raising concerns about proposed cuts to reimbursement for critical services provided by rheumatologists and other cognitive specialists.
      Rheums! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast.

      Dr. John Cush RheumNow

      2 years 9 months ago
      Rheums! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/1aSrRsLkel https://t.co/gmh155ty6w
      StillsNow Podcast August 2022 - Genetic Testing for Autoinflammatory Diseases

      Featuring a discussion with Dr. Susan Sh

      Dr. John Cush RheumNow

      2 years 9 months ago
      StillsNow Podcast August 2022 - Genetic Testing for Autoinflammatory Diseases Featuring a discussion with Dr. Susan Shenoi from Seattle Childrens Hospital https://t.co/W9e6r83R6B https://t.co/rVvDurZz2g
      Genetic Testing for Autoinflammatory Disease

      Not all patients with periodic fevers fit neatly into diagnostic categori

      Dr. John Cush RheumNow

      2 years 9 months ago
      Genetic Testing for Autoinflammatory Disease Not all patients with periodic fevers fit neatly into diagnostic categories. Some can be diagnosed as Still’s disease (based on criteria) while others can be classified as AID and some may be unclassifiable. https://t.co/E5qZS1JyAY https://t.co/PYgUbiduPF
      Review of IL-1 inhibitors in recurrent idiopathic pericarditis. While Rilonacept is FDA approved (320 mg x1 then 160 mg

      Dr. John Cush RheumNow

      2 years 9 months ago

      Review of IL-1 inhibitors in recurrent idiopathic pericarditis. While Rilonacept is FDA approved (320 mg x1 then 160 mg sc/wk), anakinra (2 mg/kg/d or 100 mg/d), canakinumab and colchicine are used https://t.co/j00yWpBbq3 https://t.co/7BK2mopssc

      Goofy But True
      Dr. Jack Cush discusses declining survival rates in the USA, FDA approvals of new COVID subvariant boosters and other odd and possibly true new research reports from the past week on RheumNow.com.
      Not all patients with periodic fevers fit neatly into diagnostic categories. Some can be diagnosed as Still’s disease (based on criteria) while others can be classified as autoinflammatory diseases (AID) and some may be unclassifiable, clinically or genetically.
      Recent review of AOSD suggests:- AOSD & SJIA are the same- Classify dz as systemic or articular- #MAS occurs in u

      Dr. John Cush RheumNow

      2 years 9 months ago

      Recent review of AOSD suggests: - AOSD & SJIA are the same - Classify dz as systemic or articular - #MAS occurs in up to 23% - Yamaguchi & Fautrel criteria are widely used - Cytokines important: IL-1, IL-6, IL-18, IL-37 - only Canakinumab is FDA-approved https://t.co/4ERA56Wqcb https://t.co/FkIWxIrwxX

      Disease Activity Scoring in AOSD

      AOSD or sJIA can have dramatic symptom severity, making it easy to gauge disease activ

      Dr. John Cush RheumNow

      2 years 9 months ago
      Disease Activity Scoring in AOSD AOSD or sJIA can have dramatic symptom severity, making it easy to gauge disease activity and response to therapy, especially at the outset. However, a validated measure of disease activity has not been agreed upon. https://t.co/oD6uDD6W8m https://t.co/KxNJeJ31h8
      Tapering biologics in Still's/Systemic JIA? 4 studies suggests after sustained inactive disease achieved, options includ

      Dr. John Cush RheumNow

      2 years 9 months ago
      Tapering biologics in Still's/Systemic JIA? 4 studies suggests after sustained inactive disease achieved, options include QOD (anakinra) dosing or dose reduction or interval prolongation (CAN & TCZ). KEY: early biologic starts https://t.co/33tjr65Gi0 https://t.co/fi6fc4NPgG
      Study of Adult-onset Still's in Western Australia. Incidence = 0.22/100 000, prevalence = 2.4/100 000. AOSD had higher r

      Dr. John Cush RheumNow

      2 years 9 months ago
      Study of Adult-onset Still's in Western Australia. Incidence = 0.22/100 000, prevalence = 2.4/100 000. AOSD had higher risk of previous liver disease (OR 2.67), serious infx (OR 4.36), joint replacement (OR 45.5), mortality not increased @ 1 & 5 yrs https://t.co/Wu0SQIMjWT https://t.co/Zvsdb2OR0y
      Still's disease in adults (AOSD) or children (sJIA) can have dramatic symptom severity, making it easy to gauge disease activity and response to therapy, especially at the outset. However, a validated measure of disease activity has not been agreed (for clinical trial and treatment assessments). A new study compares two such activity measuresin a large cohort of Still's patients.
      Myths & Misconceptions with Febrile Disorders

      Still’s disease and autoinflammatory disorders are rare condition

      Dr. John Cush RheumNow

      2 years 10 months ago
      Myths & Misconceptions with Febrile Disorders Still’s disease and autoinflammatory disorders are rare conditions unified by recurrent fevers and inflammation of skin, joints, and other organs. https://t.co/vdZWR1cwDx https://t.co/OoGIBjpZGn
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