Lung 🫁 cancer incidence and RA 44000+ RA (EIRA prospective cohort) and 216000+ matched Ctrls Swedish registries 📍56 per 100,000 📍HR 1.77 (adjusted for smoking 🚬) 📍Risk in RA + smoking 7x higher 📍Risk 2x in Sero+ vs. sero- No data on ttmt #EULAR2022 @RheumNow POS0061 https://t.co/c7eh3icW2c

B-cell depletion w/ RTX ttmt is FcγR dependant & affected by FcγRs variants 🧬 FCGR3A-158V: *encodes the allotype ⬆️ affinity for IgG1 *is associated w/ clinical and biological responses in RA and SLE. A new way to stratify pts for anti-CD20 therapy? @Yuz6Yusof #EULAR2022 OP0190 https://t.co/GPiaQXaF71

Karpouzas et al. ORAL Surveillance analysis. MACE, VTE, infections higher in those with acute and cumulative disease activity as measured by CDAI. @RheumNow #EULAR2022 POS0519 https://t.co/CtlISf2rxr

Rojas-Gimenez et al After adjusting for age, smoking, ACPA. Male sex (OR 4.2) and longer time of having RA (OR 1.08) associated with ILD @RheumNow #EULAR2022 POS0619 https://t.co/kzG76Qwe52

#EULAR2022 OP0134: Active RA increases risk of dementia Olmsted County, MINN studying RA risk factors for dementia: ⭐️886 pts incident RA, mean age 65. 103 develop dementia Risk factors: Age, rheum nodules, large jt swelling, depression/anxiety, HTN, CVD events @Rheumnow https://t.co/bUFkzBovAy

All the domains of sexual sphere are deteriorated in RA and PsA. This aspect is often overlooked and can have a significant impact on pts QoL. It may be time to assess this aspect more specifically using CSFQ-14 and propose dedicated interventions. #OP0139 @RheumNow #EULAR2022 https://t.co/l0zyBIZ1LI

#EULAR2022 OP0139 Has your pt asked about sexual fxn? Sexual dysfxn (SD) (CSFQ-14 questionnaire) and joint disease 188 AI pts, 89 controls Nearly 50% of RA pts had SD, 30% in PsA. Only 6% in control group! High depression in group, but not found as rf @RheumNow https://t.co/WvBw3cnFKC

Patient with 12 weeks inflamm-sounding arthralgias and functional impairment, high titre RF/CCP, osteitis on MRI, no clinical synovitis on exam. Do you suggest to patient to treat with methotrexate? #EULAR2022 @RheumNow

🚨 Study on MTX and male fertility Analysis of semen parameters in 🙋🏼‍♂️HC 🙋🏼‍♂️RA, PsA and PsO MTX naive 🙋🏼‍♂️Post MTX Reassuring data as NO significant effect of MTX was observed on several semen parameters. #EULAR2022 @RheumNow OP0131 https://t.co/Fq32lzAMAx

Dementia in RA associated w/ ⚡️Large joint swelling HR 2 ⚡️Any CVD HR 2.25 ⚡️Anxiety HR 1.86 ⚡️Depression HR 2.63 at any time during disease course in retrospective cohort 800+ pts #EULAR2022 @RheumNow OP0134 @MyasoedovaElena https://t.co/MLweRMEZXE