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Rheumatoid Arthritis

      Poster tours at #EULAR2024.
      A third of seropositive RA patients with long disease duration had subclinical lung abnormal

      Dr. Antoni Chan synovialjoints

      1 year 3 months ago
      Poster tours at #EULAR2024. A third of seropositive RA patients with long disease duration had subclinical lung abnormalities. This pilot study showed the potential role of lung ultrasound for the screening of subclinical ILD among these patients. Abstract 070 @RheumNow https://t.co/ypAh4idV3j
      OP0072 @RheumNow #EULAR2024

      Effects of #Upadacitinib or #Adalimumab on pain in #RA

      SELECT-COMPARE Phase 3 study

      UPA &

      Mrinalini Dey DrMiniDey

      1 year 3 months ago
      OP0072 @RheumNow #EULAR2024 Effects of #Upadacitinib or #Adalimumab on pain in #RA SELECT-COMPARE Phase 3 study UPA & ADA led to improvements in pain vs PBO PtGA & TJC28 pain improvement similar between UPA & ADA ➡️ UPA may be more effective in control of pain than ADA in RA
      #Vaccinations against #herpes #zoster in #MTX +#Upadacitinib Pts

      ▶️ #Shingrix works
      👍Pts followed to 60 months

      Janet Pope Janetbirdope

      1 year 3 months ago
      #Vaccinations against #herpes #zoster in #MTX +#Upadacitinib Pts ▶️ #Shingrix works 👍Pts followed to 60 months #EULAR2024 @eular_org @RheumNow #OP0020 https://t.co/8ORC3Nd2FK
      Wednesday was Day One at EULAR 2024 in Vienna. While the day was a slow start, the poster halls and auditoriums quickly filled with thousands of rheumatologists, eager to reunite at this international educational forum. Below are a few of my favorites from Day 1.
      Several abstracts are presenting new compounds, targeting either RA well-known inflammatory pathways or offering new mechanisms of action or therapeutic sequences; these are summarized below.
      OP0018 @RheumNow #EULAR2024

      🔎 Study looked at early RA patient trajectories through time-independent disease state

      Mrinalini Dey DrMiniDey

      1 year 3 months ago
      OP0018 @RheumNow #EULAR2024 🔎 Study looked at early RA patient trajectories through time-independent disease state 📊 Authors demonstrated 4⃣ trajectories in early RA 🦴 Inflammation in joints, blood & poor response are main discriminatory factors https://t.co/IeDIU3jg9B
      ➡️ OP0064 @RheumNow #EULAR2024

      ➡️ Non-articular pain (NAP) at early RA diagnosis & evolution over the first

      Mrinalini Dey DrMiniDey

      1 year 3 months ago
      ➡️ OP0064 @RheumNow #EULAR2024 ➡️ Non-articular pain (NAP) at early RA diagnosis & evolution over the first yr of RA treatment ➡️ NAP, esp regional NAP, common in early RA during 1st yr ➡️ NAP in axial, both upper quadrants and both lower quadrants common https://t.co/FOGcS05Z25
      OP0086 #EULAR2024 @RheumNow #EULARBest

      Pain & remission/low disease activity at 3m in pts with #RA in RA-BE-REAL

      P

      Mrinalini Dey DrMiniDey

      1 year 3 months ago
      OP0086 #EULAR2024 @RheumNow #EULARBest Pain & remission/low disease activity at 3m in pts with #RA in RA-BE-REAL Pts taking #baricitinib more likely to achieve pain control vs TNFi/other mode of action 1/2 pts achieving remission/LDA & had bari achieved ≥70% pain relief.
      TOLERA trial in RA
      RTX/ABA sequence versus RTX alone
      10pts each group
      Primary outcome was ambitious: ACPA seroconversio

      Aurelie Najm AurelieRheumo

      1 year 3 months ago
      TOLERA trial in RA RTX/ABA sequence versus RTX alone 10pts each group Primary outcome was ambitious: ACPA seroconversion No difference between ttmts (and also no seroconversion) No diff in disease activity No diff in ACPA change wt wk52 @RheumNow OP0069 #EULAR2024 https://t.co/0EM7XRzfNo
      AMPLIFIED RCT, 300+ pts

      ABA NOT (!) superior to ADA
      in dual seropositive SE+ MTX IR RA pts

      ACR50 rate high in both gp

      Aurelie Najm AurelieRheumo

      1 year 3 months ago
      AMPLIFIED RCT, 300+ pts ABA NOT (!) superior to ADA in dual seropositive SE+ MTX IR RA pts ACR50 rate high in both gps ABA 59% vs ADA 64% No new safety signal Defeating the encouraging data from smaller trials Abstr#OP0007 #EULAR2024 @RheumNow https://t.co/PvRUnpthHl
      Reminder of relevance of #Rheumatoid factor

      ⬆️RF also predicts
      cardiovascular events ⚠️
      ⬆️disease activity

      Dr Gurdeep S Dulay gurdeep_dulay

      1 year 3 months ago
      Reminder of relevance of #Rheumatoid factor ⬆️RF also predicts cardiovascular events ⚠️ ⬆️disease activity ❗️Worse outcomes #EULAR2024 #RF #RA https://t.co/kXwh682ONp
      What is new in RA at #EULAR2024?

      Below 👇🏻 my article summarising some of the exciting new MoA, therapeutic strate

      Aurelie Najm AurelieRheumo

      1 year 3 months ago
      What is new in RA at #EULAR2024? Below 👇🏻 my article summarising some of the exciting new MoA, therapeutic strategies and drugs that might (or not) shape RA future! https://t.co/ttYdElWlBY @RheumNow
      🚨New(ish) MoA in RA
      Abiprubart anti-CD40 mAb
      Blocks T cell activation
      Reduction DAS28-CRP Wk 12 -2.2 vs. -1.6 PBO
      Sm

      Aurelie Najm AurelieRheumo

      1 year 3 months ago
      🚨New(ish) MoA in RA Abiprubart anti-CD40 mAb Blocks T cell activation Reduction DAS28-CRP Wk 12 -2.2 vs. -1.6 PBO Small sample n=25 per gpe Safety profile acceptable To be continued... Abstr#OP0036 #EULAR2024 @RheumNow https://t.co/su4L7A7nGJ
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