Skip to main content
      John H Stone’s #IgG4RD lessons:
      1-It is a variable-vessel vasculitis
      2-more common/severe in males (2:1)
      3-Has no diag

      Vasco C Romao romaovc

      3 months 2 weeks ago
      John H Stone’s #IgG4RD lessons: 1-It is a variable-vessel vasculitis 2-more common/severe in males (2:1) 3-Has no diagnostic histopathology 4-IgG4 does not cause IgG4RD 5-Serum igg4 is a good biomarker 6-Rising IgG4 shouldn’t be ignored #EULAR2024 https://t.co/7p6pBqI4ue
      RA specific bone signatures (markers) detected by machine learning. Abst#0125
      Dkk1 increased in erosive RA #EULAR2024 @

      Bella Mehta bella_mehta

      3 months 2 weeks ago
      RA specific bone signatures (markers) detected by machine learning. Abst#0125 Dkk1 increased in erosive RA #EULAR2024 @RheumNow https://t.co/0A5C9LCzle
      Fibroblasts activated -> secrete chemokines which lead to granzyme K production inturn leading to damage to mitochon

      Bella Mehta bella_mehta

      3 months 2 weeks ago
      Fibroblasts activated -> secrete chemokines which lead to granzyme K production inturn leading to damage to mitochondria - release of mitochondrial DNA and production of interferon type 1 which ultimately lead to infiltrates (which contribute to the worsening saliva production) https://t.co/jZkU3SBhwc
      Single cell analysis with 12 groups
      Those patient without lymphocytic infiltrates were different!
      Mitochondria were the

      Bella Mehta bella_mehta

      3 months 2 weeks ago
      Single cell analysis with 12 groups Those patient without lymphocytic infiltrates were different! Mitochondria were the differentiator in these patients. Fibroblasts and CD8+ T cells are the most actively communicating cells. - Chemokines and ECM https://t.co/Pe0WSoYdXT
      🗣️Lowering glucocorticoids dose remains a key goal in #lupus management

      Prof @EricFMorand at #EULAR2024

      #letpush

      Matteo Piga RMD_clinic

      3 months 2 weeks ago
      🗣️Lowering glucocorticoids dose remains a key goal in #lupus management Prof @EricFMorand at #EULAR2024 #letpushbelow5 mg of prednisone in #SLE https://t.co/IeiLh2zVrT
      #EULAR2024

      Reminder …
      🔺Anti-drug antibodies cause significant variability in Therapeutic drug levels

      🔺10% ha

      Dr Gurdeep S Dulay gurdeep_dulay

      3 months 2 weeks ago
      #EULAR2024 Reminder … 🔺Anti-drug antibodies cause significant variability in Therapeutic drug levels 🔺10% have undetectable drug level after 3 months of Rx 🔺is therapeutic drug monitoring is beneficial? 🤔 https://t.co/ChgMnKPyFb
      RISK OF NON-MELANOMA SKIN CANCER WITH TNFi AND OTHER bDMARDs IN PATIENTS WITH PSORIATIC ARTHRITIS: A SWEDISH AND DANISH

      Peter Nash drpnash

      3 months 2 weeks ago
      RISK OF NON-MELANOMA SKIN CANCER WITH TNFi AND OTHER bDMARDs IN PATIENTS WITH PSORIATIC ARTHRITIS: A SWEDISH AND DANISH COHORT STUDY- despite having minimal sun 25% increase NMSC TNFis vs other bDMARDs - skin checks !@rheumnow #EULAR2024
      steroid dose 120 mg , repeated if not in remission 12 wks on background MTX - no difference between groups @rheumnow #EU

      Peter Nash drpnash

      3 months 2 weeks ago
      steroid dose 120 mg , repeated if not in remission 12 wks on background MTX - no difference between groups @rheumnow #EULAR2024 https://t.co/gkqmElfOCp