Novel Rx
Anakinra in Pediatric, Adult Still's Disease: Dr. Bella Mehta
Dr. Bella Mehta reviews abstract #1633 at the 2020 ACR annual meeting.
Meral K. El Ramahi, MD MeralElRamahiMD
4 years 11 months ago
Poll results are in! Most would like to wait for a phase III before prescribing MMF with pegloticase in refractory gout. @RheumNow #ACR20 https://t.co/45MpFliDkE
Peter Nash drpnash
4 years 11 months ago
Herpes Zoster Events with Anifrolumab in Patients with Active SLE: An Integrated Analysis of Phase 2 and Phase 3 Trials https://t.co/70oOHXihFb #SLE #zoster x 4-5 times increase in zoster
David Liew drdavidliew
4 years 11 months ago
How do we dose maintenance rituximab in AAV to optimise B cell depletion but minimise hypogammaglob?
Drug levels may be the answer. In this cohort (n=61)
trough >550ng/mL: all B cell depleted
>1000ng/mL: all got hypogammaglob
very interesting concept!
#ACR20 ABST1438 @RheumNow https://t.co/0pcl0BW2Tv
sheila RHEUMarampa
4 years 11 months ago
Data from BIOBADASER 3 showed that there was a ⬇ in the incidence of S. pneumonia-related infxns in RA pts on b/tsDMARD after receiving the stepwise combined vax scheme (conj+PS) @RheumNow #ACR20 abs1465 #VaccinesWork https://t.co/KlestmKfaO
Dr. John Cush RheumNow
4 years 11 months ago
Interim analysis of the RELIANCE registry studying effect of canakinumab (CAN) in 80 patients w/ febrile CAPS. Efficacy of CAN assessed w/ AIDA (inflam index) showing ~70% were in low activity (<9) @ACR20 Abstr#1479 https://t.co/UC2eJbpVLM https://t.co/M71s8gXZY9
Potpourri of Pathotypes of Predictors with RA Faculty
Dr. Jonathan Kay again leads an international panel of rheumatologists to elicit their opinions on key abstracts at ACR 2020. Panelists: Dr. David Liew, Dr. Eric Dein, Dr. Meral El Ramahi, Dr. Richard Conway, Dr. Sheila Reyes and Dr. Jeffrey Sparks.
Dr. John Cush RheumNow
4 years 11 months ago
1yr results using anti-IL-23 Guselkumab shows the same ACR 20/50/70 responses regardless of prior TNF inhibitor failure. #ACR20 #Abstr#1344 https://t.co/OvgJ53wwmU https://t.co/JdajDONWap
Dr. John Cush RheumNow
4 years 11 months ago
Study of 351 SLE patients from Leiden shows that SLE with Neuropsychatric disease do not have a higher mortality than lupus without CNS disease; but do have higher mortality than gen. population #ACR20 Abstr#1264 https://t.co/CmBjfUj1Ur https://t.co/WYZQDaI4yt
k dao KDAO2011
4 years 11 months ago
ACR/AF JIA guidelines presented @ACR20:
👉Initiate DMARD early over NSAID monotherapy
👉Use SQ MTX> oral MTX > SSZ/LEF
👉add biologic preferred over triple DMARD
👉DON'T use chronic low dose steroids
👉combo biologic+DMARD > biologic monoRx
https://t.co/lwoFSTuV91
@rheumnow https://t.co/wzh2LCS0dN
Pegloticase in Severe Refractory Gout: Dr. Olga Petryna
Dr. Petryna reviews several pegloticase-related abstracts presented at the ACR 2020 annual meeting, including abstracts #0683 and #0677.
Eric Dein ejdein1
4 years 11 months ago
Trivia from John Stone's pearls talk: Which is the biggest risk factor for disease flare in GCA? (All are statistically signif RFs). #ACR20 @RheumNow
Eric Dein ejdein1
4 years 11 months ago
John Stone: "The HISTORY is the Rheumatologist's scalpel." TA bx is not gold standard in diagnosis, as not fully sensitive. @RheumNow #ACR20.
David Liew drdavidliew
4 years 11 months ago
Abatacept in IgG4-RD. Plausible, but does it work?
Pilot n=10 @MGHrheumatology
ABA +<4w PNL
Some hit, some miss - but mechanistic correlates of response: Tfh2, unswitched memory B cells.
Exploring new options (w real benefit) very welcome in IgG4-RD!
#ACR20 ABST1480 @RheumNow https://t.co/0saS941Lga
k dao KDAO2011
4 years 11 months ago
#ACR20 Dr. M. Crow on Lupus #StateofArtLecture reviews treatment of SLE:
1. HCQ is the foundation of Rx
2. keep pred <7.5mg/day
3. belimumab works better when given early in disease (<2 yrs)
4. combination Rx may be needed
@rheumnow https://t.co/6zh1xkLXgN
Poster Hall