OP/Bone

k dao KDAO2011
4 years 6 months ago
We are underdiagnosing this!
In pts with persistently low ALP, think hypophoshatasia (HPP); these pts have recurrent poor healing fractures, may have CPPD, and have been refractory to standard OP Rx.
Dr. A Abelson #ACRReview @rheumnow #ACR20 https://t.co/dVptFkYXR2


k dao KDAO2011
4 years 6 months ago
Dr. A Abelson #ACRReview @rheumnow #ACR20
Romosozumab (sclerostin Ab) for OP:
👉can be used after previous treatmt with PTH analogs
👉can be used in pts with prior radiation exposure
👉not yet approved for men.
Some slides on what to choose for OP and when to choose it https://t.co/nAbOmEjx3p


Suleman Bhana, MD DrBhana
4 years 6 months ago
from #ACR20 Dr. Abbey Abelson. There was reduction in hip fractures in the US until there was drop in reimbursement for DEXA/Bone Density. @ACRheum has been advocating on Capitol Hill to restore reimbursement. Bad policy harms, but good policy can save lives.
#ACRambassador https://t.co/ARo762Vozp


Vaneet K Sandhu, MD vksandhumd
4 years 6 months ago
ARCH study -- n~4100
Romo vs Alendronate x 12 mo
Alendronate 12-24 mo
RRR 38% https://t.co/d0G7x4TqUT


Dr. Antoni Chan synovialjoints
4 years 6 months ago
How do we square up bone loss and new bone formation in AS? Are these coupled? Study from the ASSERT trial showed no relationship between baseline BMD and new syndesmophyte formation in the same vertebra @RheumNow #ACR20 Abstr#1896

sheila RHEUMarampa
4 years 7 months ago
Study of Chinese pts on long-term GCs by Dr CC Mok: DEN >> ALN in ⬆spinal BMD & suppressing bone turnover markers after 1yr tx.
No sig. diff in AEs among grps.
Limits: Open-label,small ss,short tx dur'n, not powered for fractures @RheumNow #ACR20 abs1442 https://t.co/m8mT0hMPN8


k dao KDAO2011
4 years 7 months ago
#ACRKnowledgeBowl #acr20 @rheumnow
This % of bone loss is assc with a T-score -1.5 on a DXA
Male Osteoporosis: Dr. Kathryn Dao
Dr. Kathryn Dao reviews abstract #0533 presented at the 2020 ACR annual meeting.

Eric Dein ejdein1
4 years 7 months ago
Re Abs#760: Bone erosions in +CCP not predictive of development of IA. You have a pt with no synovitis, but +CCP, small bone erosion on standing foot xray. Do you treat? #ACR20 @Rheumnow

Eric Dein ejdein1
4 years 7 months ago
Dr Hansen at 3S008 on "Bone for the Holidays": individualize the decision for drug holidays - here are the key questions: #acr20 @Rheumnow https://t.co/lMHtYW4OzE


Bella Mehta bella_mehta
4 years 7 months ago
Great talk by @lovetolearn27 Prosthetic joint infection doubles the risk of venous thromboembolism after revision of knee replacement. 15 yr data New York state -25K revisions! @RheumNow #ACR20 ABS#0960 https://t.co/4PHHSEstKs


Mrinalini Dey DrMiniDey
4 years 7 months ago
Presenting work by @drdj & I showing "Risk Factors for Lumbar Vertebral #Osteoporosis Do Not Reflect Factors Traditionally Associated with Osteoporosis at the Hip."
🗓️Session: #Epidemiology & #PublicHealth Posters II
⏰1400 GMT/ 0900 ET today!
🗒️Abs#0544
#DEXA #ACR20 @RheumNow

sheila RHEUMarampa
4 years 7 months ago
Kaiser Permanente AFF study takeaways:
- risk of atypical #fracture ⬇ vs. other clinical fractures
- ⬆ risk in Asians
- consider drug holidays for pts on bisphosphonates
@RheumNow #ACR20 https://t.co/mq9zIh2iD5


Rheum Cat rheum_cat
4 years 7 months ago
@JYazdanyMD @UWRheum @r_burmester Black, et al - cont'd
277 atypical femur fx events
Risk increased w longer duration of bisphosphonate use
Risk decreased after bisphosphonate discontinuation
Asians had a higher risk than Whites.
#ACR20 #ACRambassador