Novel Rx
4 years ago
Interim analysis of the RELIANCE registry studying effect of canakinumab (CAN) in 80 patients w/ febrile CAPS. Efficacy of CAN assessed w/ AIDA (inflam index) showing ~70% were in low activity (<9) @ACR20 Abstr#1479 https://t.co/UC2eJbpVLM https://t.co/M71s8gXZY9
Potpourri of Pathotypes of Predictors with RA Faculty
Dr. Jonathan Kay again leads an international panel of rheumatologists to elicit their opinions on key abstracts at ACR 2020. Panelists: Dr. David Liew, Dr. Eric Dein, Dr. Meral El Ramahi, Dr. Richard Conway, Dr. Sheila Reyes and Dr. Jeffrey Sparks.
4 years ago
1yr results using anti-IL-23 Guselkumab shows the same ACR 20/50/70 responses regardless of prior TNF inhibitor failure. #ACR20 #Abstr#1344 https://t.co/OvgJ53wwmU https://t.co/JdajDONWap
4 years ago
Study of 351 SLE patients from Leiden shows that SLE with Neuropsychatric disease do not have a higher mortality than lupus without CNS disease; but do have higher mortality than gen. population #ACR20 Abstr#1264 https://t.co/CmBjfUj1Ur https://t.co/WYZQDaI4yt
ACR/AF JIA guidelines presented @ACR20:
👉Initiate DMARD early over NSAID monotherapy
👉Use SQ MTX> oral MTX > SSZ/LEF
👉add biologic preferred over triple DMARD
👉DON'T use chronic low dose steroids
👉combo biologic+DMARD > biologic monoRx
https://t.co/lwoFSTuV91
@rheumnow https://t.co/wzh2LCS0dN
Pegloticase in Severe Refractory Gout: Dr. Olga Petryna
Dr. Petryna reviews several pegloticase-related abstracts presented at the ACR 2020 annual meeting, including abstracts #0683 and #0677.
4 years ago
Abatacept in IgG4-RD. Plausible, but does it work?
Pilot n=10 @MGHrheumatology
ABA +<4w PNL
Some hit, some miss - but mechanistic correlates of response: Tfh2, unswitched memory B cells.
Exploring new options (w real benefit) very welcome in IgG4-RD!
#ACR20 ABST1480 @RheumNow https://t.co/0saS941Lga
#ACR20 Dr. M. Crow on Lupus #StateofArtLecture reviews treatment of SLE:
1. HCQ is the foundation of Rx
2. keep pred <7.5mg/day
3. belimumab works better when given early in disease (<2 yrs)
4. combination Rx may be needed
@rheumnow https://t.co/6zh1xkLXgN
Poster Hall