Dr England presents on multimorbidity in RA, PsA, gout, and OA within RISE registry. Highly prevalent in all 4 but most pronounced in gout and RA. Critical to recognise and manage. @rheumnow #ACR20 Abstr#1466 https://t.co/XtwIfJnVXV

Liraglutide as a Potential Intra-Articular Treatment for Cartilage Regeneration in Osteoarthritis: In Vitro and In Vivo Studies Supporting a Pro-Chondrogenic Effect https://t.co/T9IqF7E00Z #OA #DMOAD a potential DMOAD in mice

• Liraglutide as a Potential Intra-Articular Treatment for Cartilage Regeneration…

@Janetbirdope @RheumNow @CRASCRRheum This study is a follow-on to an existing body of evidence re: vitamin K-dependent proteins ("Gla" proteins) in #OA, as well as warfarin VK antagonist effects, and agnostic discovery in a GWAS. The findings hold including in studies unrelated to access to care and a small RCT.

It's only now we have choices to warfarin that we can realise the effect of vit K blockade on OA. Nested case-control (AF pts, UK primary care): warfarin has risk vs DOAC for end-stage OA (via joint replacement) aOR 1.25 esp knee aOR 1.48 @Tuhina_Neogi #ACR20 ABST0934 @RheumNow https://t.co/XVLG8kIL0W

Plenary session: Dr Ballal presents data showing #warfarin use incr. risk of knee/hip replacements, compared to #DOACs - Nest case-control study in UK THIN database - Risk increases w/ duration of use - Indicates need for well-powered RCT of vit K in OA Abs#0934 #ACR20 @RheumNow https://t.co/YyxDjNQEjx

Amazing to see a plenary by a 1st year fellow @BU_BMC_Rheum - Vit K is important in preventing #OA progression - obs study #Warfarin has higher knee and hip replacement risk compared to #DOACs #ACR20 @RheumNow ABS#0934 https://t.co/0IUS8QvzI4

Abst#0934 by Dr. Ballal at BU looks at the role of vitamin K deficiency in OA development. Warfarin use with 57% increased risk of TKA/THA compared to NOAC, though diminished when accounting for signif practice variation in these patients @Rheumnow #ACR20 https://t.co/PsESoeurKF

Scoring hand x-rays for Sharp scores is painfully tedious and not always perfectly consistent. Why not get a computer to do it? Turns out you can - a deep adaptive machine learning model does as well as a human, each x-ray in literally one second. #ACR20 ABST0493 @RheumNow https://t.co/SvqkaFy8XZ