Anti-Rheumatic Rx
3 years 1 month ago
Infxn risk of 1st year on rituximab for mod to severe SLE vs standard-of-care
🔹Most common SoC Rx: MMF, Aza, and/or cyclophosphamide
🔹🚫significant diff
🔹RTX pts = ⬆️dz duration, ⬆️# of prior meds, ⬇️maintenance steroid dose
https://t.co/AYQFXqlubl
#ACR21 Abst1288 @RheumNow
Highlight reports from Sunday, Day 2 at ACR Convergence included:
VITAL Trial: Vitamin D and n-3 Fatty Acid Supplements Protect Against Autoimmune Disease
Abstract 0957 – Dr. Karen…
3 years 1 month ago
#ACR21 #Abstr1462 More case against Low dose Hydroxychloroquine as could ⬆️ risk of #lupus flares. Adjusted risk as below:
Weight =>80kg, <400mg/d dose (OR 8.3)
Weight <80kg, <300mg/d dose (OR 2.6) @RheumNow https://t.co/bTRMJDoSoI https://t.co/yzopiO3Kbo
3 years 1 month ago
Alcohol and MTX don't go along!
In a cohort of 1000+ early RA
Factors associated w/
1️⃣Nausea
Female OR 2
🍺 Alcohol OR 1.44
DAS28CRP OR 1.16
2️⃣Alopecia
Age OR 4.87
🍺 Alcohol OR 1.98
HAQ score OR 1.62
#Abst1444 #ACR21 @RheumNow https://t.co/zZG6aFR1SX
3 years 1 month ago
👉HCQ dose < 400 mg/d are assc with SLE flare. Lower doses of HCQ may decrease risk of retinopathy. 👉For >80 kg (176 lbs), any dose < 400 mg/day is assc with increased odds of flare
(HCQ blood levels not measured)
Abst#1462 #ACR21 @rheumnow https://t.co/5tx3kruT8W
3 years 1 month ago
@ericdeinmd Although the MTX/alopecia - nausea poster was interesting. Abst#1444 #ACR21
Factors assc w/MTX- nausea/alopecia:
👉female sex
👉EtOH use
👉higher disease activity
👉belief that the med will cause it
(older age assc w/⬇️risk of nausea) https://t.co/XDKFhvN0V1
@rheumnow
3 years 1 month ago
#ACR21 Ab#1444 @AhmadSherbini. Factors ass w/ nausea & alopecia in MTX
⭐️Nausea & alopecia: ♀️, 🥃, activity score are risk factors
▶️EtOH highlights importance of folic acid in these pts!
@Rheumnow https://t.co/6UNUVh5ZW8 https://t.co/lxB2z2lXtu
3 years 1 month ago
Love-hate relationship with #methotrexate. Side effects are common ex nausea/GI in 1/3 and alopecia in women. ?if you ask do you get more AES. Tough to treat especially SEs are early. ?Coach pt to help w persistence abst1444# @RheumNow #ACR21 https://t.co/NDQDVz8lk2
3 years 1 month ago
Abst1344 #ACR21 @RheumNow observational study of pts w/PsA treated w/b&tsDMARD:pts who achieve MDA (22.8% of pts at 6 mo) more likely to maintain the initiated bDMARD or tsDMARD Rx & less likely to switch from the initiated bDMARD/tsDMARD https://t.co/egFDHV3eQs