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      Are Emulation Trials a Fantasy?

      Are these ‘trials’ helpful, despite the biases that occur with observational data,

      Dr. John Cush RheumNow

      9 months 2 weeks ago
      Are Emulation Trials a Fantasy? Are these ‘trials’ helpful, despite the biases that occur with observational data, or do they truly mimic the results of randomized controlled trials (RCTs)? https://t.co/x6NogGQksW https://t.co/f8o8N55tlJ
      axSpA: Moving the needle in time to diagnosis

      The journey to axial spondyloarthritis (axSpA) diagnosis is often prolong

      Dr. John Cush RheumNow

      9 months 2 weeks ago
      axSpA: Moving the needle in time to diagnosis The journey to axial spondyloarthritis (axSpA) diagnosis is often prolonged and challenging. Understanding the factors contributing to the delays is important to improve the clinical, psychological, social and economic outcomes.… https://t.co/wnwtj8jj0q https://t.co/Pds2uxVfJV
      So really, are JAKs Safe?
      Assessment and management of axSpA

      Dr. Antoni Chan reports on abstract 0818, Defining BASDAI Cut-offs for Disease Activ

      Dr. John Cush RheumNow

      9 months 2 weeks ago
      Assessment and management of axSpA Dr. Antoni Chan reports on abstract 0818, Defining BASDAI Cut-offs for Disease Activity States in Axial Spondylarthritis – Results from the EuroSpA Collaboration, and abstract 0819, The Assessment of SpondyloArthritis International Society… https://t.co/ropQJdElyb https://t.co/IVn5u2l7iP
      RheumNow’s expanded coverage of the #ACR24 meeting is sponsored in part by Bristol Myers Squibb and UCB. All content i

      Dr. John Cush RheumNow

      9 months 2 weeks ago
      RheumNow’s expanded coverage of the #ACR24 meeting is sponsored in part by Bristol Myers Squibb and UCB. All content is chosen by RheumNow and its faculty.
      Are we under-monitoring in scleroderma ILD?

      Dr. Janet Pope discusses abstract 0678, Patients with Interstitial Lung Dis

      Dr. John Cush RheumNow

      9 months 2 weeks ago
      Are we under-monitoring in scleroderma ILD? Dr. Janet Pope discusses abstract 0678, Patients with Interstitial Lung Disease Due to Systemic Sclerosis or Rheumatoid Arthritis Need Monitoring More Frequently Than Annually, and abstract 0706, Single Center Prospective Cohort of… https://t.co/1y1VXGvqjp https://t.co/4ofh45cYwq
      Treatment Strategies in RA
      Hypoxia seems to exacerbate neutrophil activation by ANCA

      - enhanced F-Actin polymerization
      - enhanced NET formation

      Brian Jaros, MD Dr_Brian_MD

      9 months 2 weeks ago
      Hypoxia seems to exacerbate neutrophil activation by ANCA - enhanced F-Actin polymerization - enhanced NET formation Could hypoxia predilection in certain tissues (kidney, lung) lead to the AAV phenotypic disease patterns? @RheumNow #ACR24 https://t.co/KxaeMvkd2t
      Prior studies have shown that IFN is increased in non-lesional skin of SLE pts.

      In this study, they found a ⬆️ exp

      sheila RHEUMarampa

      9 months 2 weeks ago
      Prior studies have shown that IFN is increased in non-lesional skin of SLE pts. In this study, they found a ⬆️ expression of IFN stimulated genes (ISGs) in pts w/ a history of CLE. No correlation w/ CLASI act & IFN scores but only few pts. @RheumNow #ACR24 abs2678 https://t.co/cPT6yPkoCb
      Prof Petri reports the ff predictors of fracture in SLE:
      -older age
      -Caucasian race
      -female sex

      ⚠️ Prednisone (but

      sheila RHEUMarampa

      9 months 2 weeks ago
      Prof Petri reports the ff predictors of fracture in SLE: -older age -Caucasian race -female sex ⚠️ Prednisone (but not recent IM triamcinolone or IV methylpred) is a MAJOR risk factor. When possible, avoid prednisone! @RheumNow #ACR24 #ACRbest abs2679 @rheumarhyme https://t.co/q2NMRaYsAF
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