Rheumatoid Arthritis
  David Liew drdavidliew
            3 years 5 months ago 
          
         
          Treat-to-target in RA is held with an almost religious fervour in rheumatology, but it's really hard to follow religiously. What happens if you're only T2T observant on the high holidays?
Answer: the world's not too bad!
(2y is bit short I realise)
POS0111 #EULAR2022 @RheumNow https://t.co/Boh74JmsP3
        
        
  Dr. John Cush RheumNow
            3 years 5 months ago 
          
         
          Watch: Treatment of Pre-RA: Is Early Already Too Late?
Dr. Aurelie Najm reviews abstract OP0070 presented at the #EULAR2022 meeting.  #MedEd 
https://t.co/ep4lgtZYcT https://t.co/LTx1RMGdkv
        
        
      
  Eric Dein ericdeinmd
            3 years 5 months ago 
          
         
          #EULAR2022 OP0067:
Depression is a major risk factor (6X!) for mortality in RA. Study may show some bias in the methods, but critical findings for all rheumatologists to consider
@RheumNow 
https://t.co/leeY9zAx4T
        
        
  Eric Dein ericdeinmd
            3 years 5 months ago 
          
         
          #EULAR2022
Ultrasound may be used to evaluate patients with RA (POS1393) and SSc (POS1394)
👁️Look for B-lines and pleural irregularity
Will require training of MSKUS rheumatologists, but another potential application of US in clinical practice
@RheumNow @MymaAlbaydaMD @USSONAR_Rh https://t.co/qtnBviKA3w
        
        
  Dr. John Cush RheumNow
            3 years 5 months ago 
          
         
          Watch: EULAR 2022 - Day 1 Faculty Recap Pane
Drs. Jack Cush, Eric Dein and Kathryn Dao discuss highlights from day 1 at #EULAR2022 - Guidelines, Lupus, and more.
https://t.co/OBLt7dOMa3 https://t.co/lHmEOIFIGa
        
        
      
  Dr. John Cush RheumNow
            3 years 5 months ago 
          
         
          A Big Leap in Modulating Rheumatoid Disease
Intervention in individuals predisposed to develop rheumatoid arthritis (RA), with a holy grail of prevention of RA, has long been a hot topic.
https://t.co/QHK7c3Qhz6 https://t.co/jFR9wDCD8o
        
        
      
  Aurelie Najm AurelieRheumo
            3 years 5 months ago 
          
         
          CTD associated ILD 🫁:
lncRNA ENST00000604692 detected in PBMCs is associated with CTD-ILD and can distinguish SSc-
ILD and RA-ILD vs. non ILD patients with AUC 0.79. 
As many lncRNA, unknown if biomarker only or has a pathogenic role.
@RheumNow OP0114 #EULAR2022 https://t.co/sR4GmaMkXD
        
        
  Aurelie Najm AurelieRheumo
            3 years 5 months ago 
          
         
          Lung 🫁 cancer incidence and RA
44000+ RA (EIRA prospective cohort) and 216000+ matched Ctrls Swedish registries
📍56 per 100,000 
📍HR 1.77 (adjusted for smoking 🚬)
📍Risk in RA + smoking 7x higher 
📍Risk 2x in Sero+ vs. sero-
No data on ttmt
#EULAR2022 @RheumNow POS0061 https://t.co/c7eh3icW2c
        
        
  Aurelie Najm AurelieRheumo
            3 years 5 months ago 
          
         
          B-cell depletion w/ RTX ttmt is FcγR dependant & affected by FcγRs variants 🧬
FCGR3A-158V:
*encodes the allotype ⬆️ affinity for IgG1 
*is associated w/ clinical and biological responses in RA and SLE.
A new way to stratify pts for anti-CD20 therapy?
@Yuz6Yusof #EULAR2022 OP0190 https://t.co/GPiaQXaF71
        
        
  

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