
B-cell depletion w/ RTX ttmt is FcγR dependant & affected by FcγRs variants 🧬
FCGR3A-158V:
*encodes the allotype ⬆️ affinity for IgG1
*is associated w/ clinical and biological responses in RA and SLE.
A new way to stratify pts for anti-CD20 therapy?
@Yuz6Yusof #EULAR2022 OP0190 https://t.co/GPiaQXaF71
Links:
02-06-2022