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Anti-Rheumatic Rx

      EULAR treats its attendees to a wonderful lunch each day – Schnitzel, gnocchi, goulash at lunch after muffins and coffee in the morning. It's no wonder the meeting has been a lively one, well attended with a wealth of stimulating ideas, research and discussion. Here are a few of my favorite abstracts and presentations from today, day 3 in Vienna.
      500+ pts AxSPA
      No difference in drug discontinuation between IL-17i, TNFi, IL23i over time
      Adjusted for CRP, co-medicati

      Aurelie Najm AurelieRheumo

      1 year 4 months ago
      500+ pts AxSPA No difference in drug discontinuation between IL-17i, TNFi, IL23i over time Adjusted for CRP, co-medication w/ MTX + classic covariates IL-17i and IL-23i had experienced a higher number bDMARD failures #EULAR2024 POS0259 @RheumNow https://t.co/F3B6uXyAca
      Multi-modal analysis of rheumatoid arthritis (RA) synovitis pathotypes enables more accurate choices of first line cDMARDs treatment, suggesting a predictive value to synovial biopsy. 
      Leflunomide for #PMR?

      ✅ #Leflunomide FAR more effective than #MTX in #polymyalgia #rheumatica

      V fast withdrawal of #

      Janet Pope Janetbirdope

      1 year 4 months ago
      Leflunomide for #PMR? ✅ #Leflunomide FAR more effective than #MTX in #polymyalgia #rheumatica V fast withdrawal of #prednisone #LEF ~4 to 5 months #MTX 30 mos! ⬇️flares w LEF 😮 #EULAR2024 @RheumNow @eular_org @SebaUltraTrail https://t.co/2hk0yMH6gY
      Day 2 at EULAR 2024 was a big poster day for many with several good sessions and oral presentations on Preventing RA, new vasculitis therapies and a session devoted to the 50th anniversary of the Moll & Wright Criteria.
      PsA Treatment: is Earlier Better?
      Analysis of French claims data, found over half of women initiating oral bisphosphonates (BP) between 2015 and 2020 discontinued treatment for at least one year, which was associated with a 12% increase in fracture risk. While not recommended, 42.5% of women initiating Dmab discontinued treatment for at least one year, which almost doubled their fracture risk. No increased risk was observed for long term discontinuation of IV BP.
      Dual seropositivity (rheumatoid factor and/or anti-citrullinated protein antibodies) as well as shared epitope are known to be associated with poor prognosis and structural damage in RA.
      What happens when RA patients only on csDMARDs want to stop their meds?

      in BIO-FLARE, only half flared within 6mo of st

      David Liew drdavidliew

      1 year 4 months ago
      What happens when RA patients only on csDMARDs want to stop their meds? in BIO-FLARE, only half flared within 6mo of stopping all csDMARDs suddenly. They’ve got a clinical predictive model. Many milder patients ask, and could benefit! #EULAR2024 POS0068 John Isaacs @RheumNow https://t.co/B7ZjP5Pj70
      OP0201- clinical characteristics of pts failing ≥2 b/tsDMARDs

      D2T RA pts characterised by
      ⏰ Earlier disease
      ⏰ Lat

      Mrinalini Dey DrMiniDey

      1 year 4 months ago
      OP0201- clinical characteristics of pts failing ≥2 b/tsDMARDs D2T RA pts characterised by ⏰ Earlier disease ⏰ Later initiation of DMARD therapy Discontinuation of drugs mainly due to inefficacy regardless of number of drug lines or MOAs used #EULAR2024 @RheumNow
      OP0140-When should we give #pneumococcal #vaccine to pts starting MTX?

      Study in RA:PCV13 vaccine given 1 month BEFORE s

      Mrinalini Dey DrMiniDey

      1 year 4 months ago
      OP0140-When should we give #pneumococcal #vaccine to pts starting MTX? Study in RA:PCV13 vaccine given 1 month BEFORE starting MTX leads to higher immunological response at 1m, vs pts vaccinated simultaneously w MTX ⏩Vaccinate patients before starting MTX! @RheumNow #EULAR2024
      Combination of GOL/MTX was not significantly superior in reducing PASDAS-measured disease activity at 24 weeks. First l

      Dr. Antoni Chan synovialjoints

      1 year 4 months ago
      Combination of GOL/MTX was not significantly superior in reducing PASDAS-measured disease activity at 24 weeks. First line treatment of early, DMARD naïve PsA with MTX 25 mg/week and CS produced effective disease control. There was low utilisation of bDMARDs at 52 weeks in both… https://t.co/aEg9rw4evM https://t.co/prDtnHm793
      Can you ⬇️

      #Glucocorticoids or #immunesuppressive in #SLE & change am’t of damage

      From Asia Pacific #lupus

      Janet Pope Janetbirdope

      1 year 4 months ago
      Can you ⬇️ #Glucocorticoids or #immunesuppressive in #SLE & change am’t of damage From Asia Pacific #lupus collab (Biologics not included) Compared 7.5 mg #prednisone or less Or DMARD 1/2 flared after LLDAS ⬇️dose didn’t prevent damage #EULAR2024 @eular_org @RheumNow https://t.co/QmjEz87Cvw
      OP0137 is comparative analysis of clinical efficacy & drug retention of b/tsDMARDs

      >1/2 D2T RA pts starting JAKi

      Mrinalini Dey DrMiniDey

      1 year 4 months ago
      OP0137 is comparative analysis of clinical efficacy & drug retention of b/tsDMARDs >1/2 D2T RA pts starting JAKi, RTX, IL-6Ri, or TNFi, but ~1/3 w abatacept, achieved remission or low disease activity in 6m & maintained consistent drug retention for 2yrs @RheumNow #EULAR2024
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