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      Another excellent oral presentation from UPMC myositis center by Shiri Keret at #EULAR2024. She showed that many myositi

      Rohit Aggarwal docrota

      1 year 3 months ago
      Another excellent oral presentation from UPMC myositis center by Shiri Keret at #EULAR2024. She showed that many myositis patient may have normal CK despite muscle weakness. However, CK is associated with outcomes over time even in patients with normal or near normal CK,… https://t.co/nAoUo8fcXh https://t.co/J8iZG4eESP
      ✅ Updated pipeline of phase 2 & 3 trials in #Lupus ⬇️ #EULAR2024
      Please let me know if something is missing or

      Laurent ARNAUD Lupusreference

      1 year 3 months ago
      ✅ Updated pipeline of phase 2 & 3 trials in #Lupus ⬇️ #EULAR2024 Please let me know if something is missing or incorrect 👍 https://t.co/ruuKYmAvYj
      John H Stone’s #IgG4RD lessons:
      1-It is a variable-vessel vasculitis
      2-more common/severe in males (2:1)
      3-Has no diag

      Vasco C Romao romaovc

      1 year 3 months ago
      John H Stone’s #IgG4RD lessons: 1-It is a variable-vessel vasculitis 2-more common/severe in males (2:1) 3-Has no diagnostic histopathology 4-IgG4 does not cause IgG4RD 5-Serum igg4 is a good biomarker 6-Rising IgG4 shouldn’t be ignored #EULAR2024 https://t.co/7p6pBqI4ue
      RA specific bone signatures (markers) detected by machine learning. Abst#0125
      Dkk1 increased in erosive RA #EULAR2024 @

      Bella Mehta bella_mehta

      1 year 3 months ago
      RA specific bone signatures (markers) detected by machine learning. Abst#0125 Dkk1 increased in erosive RA #EULAR2024 @RheumNow https://t.co/0A5C9LCzle
      Fibroblasts activated -> secrete chemokines which lead to granzyme K production inturn leading to damage to mitochon

      Bella Mehta bella_mehta

      1 year 3 months ago
      Fibroblasts activated -> secrete chemokines which lead to granzyme K production inturn leading to damage to mitochondria - release of mitochondrial DNA and production of interferon type 1 which ultimately lead to infiltrates (which contribute to the worsening saliva production) https://t.co/jZkU3SBhwc
      Single cell analysis with 12 groups
      Those patient without lymphocytic infiltrates were different!
      Mitochondria were the

      Bella Mehta bella_mehta

      1 year 3 months ago
      Single cell analysis with 12 groups Those patient without lymphocytic infiltrates were different! Mitochondria were the differentiator in these patients. Fibroblasts and CD8+ T cells are the most actively communicating cells. - Chemokines and ECM https://t.co/Pe0WSoYdXT
      🗣️Lowering glucocorticoids dose remains a key goal in #lupus management

      Prof @EricFMorand at #EULAR2024

      #letpush

      Matteo Piga RMD_clinic

      1 year 3 months ago
      🗣️Lowering glucocorticoids dose remains a key goal in #lupus management Prof @EricFMorand at #EULAR2024 #letpushbelow5 mg of prednisone in #SLE https://t.co/IeiLh2zVrT
      #EULAR2024

      Reminder …
      🔺Anti-drug antibodies cause significant variability in Therapeutic drug levels

      🔺10% ha

      Dr Gurdeep S Dulay gurdeep_dulay

      1 year 3 months ago
      #EULAR2024 Reminder … 🔺Anti-drug antibodies cause significant variability in Therapeutic drug levels 🔺10% have undetectable drug level after 3 months of Rx 🔺is therapeutic drug monitoring is beneficial? 🤔 https://t.co/ChgMnKPyFb
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