Lupus
alexa meara lexmeara
4 years 11 months ago
Can we use urine testing ( and all the cells, proteins, complements, DNA, rna) to predict LN response? Plenary II @SalemAlmaani @BradRovin @RheumNow #ACR20 @OSUWexMed
Yu (Ray) Zuo RayZuoMD
4 years 11 months ago
Great talk #ACR20 Integrating bulk and single-cell RNA-sequencing @Kahlenberglab identifies clinically actionable 5-gene signatures that can effectively differentiate DM from cutaneous lupus lesions. @RheumNow @UMIntMed Also out in @JCI_insight https://t.co/uYS6OJH0Hf https://t.co/KR0wwDb5BK
Janet Pope Janetbirdope
4 years 11 months ago
50% use septra/bactrim in SLE if immunesuppressed. I don’t use it unless if frequent serious infections or bad lungs as I am not convinced about the risk of PCP/PJP v risk of septra with adverse rxns in SLE. I await an admin database to give me the data @RheumNow #ACR20 https://t.co/3s2S9fIUVe
Robert B Chao, MD doctorRBC
4 years 11 months ago
Dr. Aggarwal Abs#0955 showed efficacy of IVIG in tx of Dermatomyositis.
How/when do you use IVIG for tx of DM?
@RheumNow #ACR20
Robert B Chao, MD doctorRBC
4 years 11 months ago
Efficacy of IVIG in Dermatomyositis Treatment
1st Placebo controlled RCT
1️⃣79% responder by total improvement score vs. 44%
2️⃣Efficacy sustained thru wk 40
3️⃣6% serious AE - thromboembolic event
@RheumNow #ACR20 Abs#0955 #ACRbest https://t.co/715h1UkZ9X
sheila RHEUMarampa
4 years 11 months ago
ProDERM study:10% IVIG is effective and safe in pts with DM. First large PBO-controlled, randomized ph 3 trial. @RheumNow #ACR20 abs0995 #ACRbest https://t.co/aJyASaAMlJ
Mrinalini Dey DrMiniDey
4 years 11 months ago
#HCQ assoc. w/ ↓platelet activity & ↑vascular health in #SLE:
- 132 patients, 108 on HCQ
- Ex-vivo expts show ↓platelet aggregation & downregulation of platelet functional pathways
- HCQ may improve vascular health in SLE
Abs#0870 #ACR20 @RheumNow
https://t.co/ST9n2HGyhM
Mrinalini Dey DrMiniDey
4 years 11 months ago
Data from MUSE & TULIP trials of #anifrolumab in #SLE show increased risk of #herpeszoster when compared to placebo. Most HZ events mild-moderate, cutaneous and resolved without discontinuation of drug.
#RheumTwitter #lupus
Abs#0849 #ACR20 @RheumNow
https://t.co/8a6OcZmOso
HCQ and QTc Prolongation: Dr David Liew
Dr. David Liew reviews abstracts #0431 presented at the ACR 2020 annual meeting - and shares the results of the Twitter poll he conducted asking when prescribing HCQ, is an EKG routinely ordered either before or doing.
Dr. John Cush RheumNow
4 years 11 months ago
HCQ Not Associated with QTc Length in SLE and RA Patients: Dr. Janet Pope @Janetbirdope #ACR20
https://t.co/zPIaFIiqr5 https://t.co/Wk8YQpIpo7
Healthcare Disparities: Dr. Eric Dein
Dr. Eric Dein discusses abstracts #0049 (accessing patient portals) and #0045 (assessing rashes in patients of color in lupus) presented Friday at the 2020 ACR annual meeting.
Janet Pope Janetbirdope
4 years 11 months ago
Congrats to Dr S Izuka a clinical Rheumatolgy fellow for making a press release. Looking forward to full presentation next week. We published SLE pts had more adverse drug reactions than RA so I try to avoid sulfa drugs in SLE JRheum 2003;30:480-4 #ACR2020 https://t.co/spr6FsS1xg
Does Hydroxychloroquine Hurt the Heart? Dr. Jonathan Kay
Boston-based rheumatologist Dr. Jonathan Kay examines an ACR 2020 study (abstract #0431) looking at whether hydroxychloroquine use has injured patients' hearts.
Racial Disparities - Stroke, Heart Attacks Risks Higher in SLE: Dr. Kathryn Dao
Dr. Kathryn Dao discusses abstract #0433 presented Friday at the 2020 ACR annual meeting.
Dr. John Cush RheumNow
4 years 11 months ago
Among a 402 pt PSS cohort, 10% fmet 2019 EULAR/ACR SLE Criteria. SSc-SLE overlap pts more likely to be female, AfricanAmerican, limited cut.SSc, U1RNP and have similar rates of severe SSc-specific organ damage /mortality. #ACR20 Abstr#0401 https://t.co/CVcFyx9AxS https://t.co/3SAKZ9CZGS
Poster Hall