Olmstead County (Mayo) population study shows 47 lupus nephritis (LN) pts betw 1976-2018. Incidence doubled from 1980s (0.6 per 100K) to 2018 (1.2/100K); with women of childbearing age as the most affected group. #ACR20 Abstr#0274 https://t.co/uhAMd0EtJl

Dr. C Mohan @UTSWNews #ACR20 @rheumnow reviews IFN in SLE: 👉Diff't IFN assc w/diff't lupus manifestions 👉⬆️stim endosomal DNA/RNA sensors RLR7,8,9 may drive SLE 👉TLR7 & 9 in B cells impt for germinal ctrs & Ab prod’n 👉TLR7 is X-linked 👉IFNsig not track w/dz activity https://t.co/3KK3UvH8Ka

Year in review @JYazdanyMD take home points from 2 key positive trials (finally!) in SLE this year #ACR20 @RheumNow https://t.co/74SVwNavPK

#ACR20 Abstr#0433 #PlenaryACR Georgia SLE registry 336 pts ⬆️stroke/isch heart dz with: 👉3X stroke risk and 24X IHD risk for black pts 👉predictors stroke: black race, DLE, renal dz 👉predictors IHD: age>65, black race, neuro & immuno d/o (e.g, APAs) @RheumNow https://t.co/u6Ky7r0FYF

Plenary session 1 no#2F011 #ACR20 @rheumnow Black #SLE patients have a 3 fold higher stroke and 24 fold higher Ishemic Heart Disease risk! https://t.co/AYtiXk7pDa

#hydroxychloroquine is not a ‘cutie’ drug. E Park et al showed that HCQ does not increase QT interval in RA & SLE patients including if on other meds that may affect QT but known heart disease excluded from study #ACR20 #ACR2020 @RheumNow abstr#432 @CRASCRRheum https://t.co/FGVPknmj5q

Beautiful poster and fascinating research from @chriswincup et al showing immune cellular iron deficiency in patients with #SLE. Time to add iron supplementation as part of standard #lupus therapy? https://t.co/Uf81KXbSM0 Abs#0294 #ACR20 @RheumNow https://t.co/z5SUjWFkdD

• Tired T-Cells and Monocytes with Malaise: Investigating the Links Between Cellu…

ANA antibodies in longitudinal #SLE cohort: - 759 patients - 84.8% remained ANA+ve during 5yr followup period - Pts w/ at least one -ve ANA in first 5yrs had milder disease (lower SLEDAI-2K, less steroid, fewer autoantibodies) Abs#0251 #ACR20 @RheumNow https://t.co/U7JbNpJA3w

• Dynamics of Anti-Nuclear Antibodies in a Longitudinal Study of a Large Systemic…

Dr. G Gilkeson #Klempererlecture #ACR20 @rheumnow There is a lupus gradient b/t Africa and US: we are seeing more SLE in the US (genetics? environmental? diet?)

Dr. Gilkerson in 2F010- Lupus in Unusual Places at #ACR20- Is it environmental or genetics that explain differences between African and African-Amer populations? Study the population (Sierra Leone), but do so with cultural sensitivity. @RheumNow https://t.co/B1ikkQgCuk