Dr Rubin of @NEJM on #vaccine development: safety and efficacy very important. Great keynote lecture! @RheumNow #ACR20 https://t.co/hVR2rmOMNp

Inflammation is not a single entity, and the imperative to dissect it carefully is so great in irAEs - in both treatment and measurement. "I'm attempting to stir the pot" - @LCalabreseDO - and there really is plenty to think about. https://t.co/8C6RbMI2l9

One of my #ACR20 highlights about to start - irAE Study Group, hosted by @CCalabreseDO & @NohaMDAnderson Imminent paradigm definition by @LCalabreseDO: one of the biggest challenges in the field: how to target therapies in irAEs, to maintain cancer response #ACR2020 @RheumNow https://t.co/WzFbCc8TuT

Dr. Siri will see you now...🤖 Machine learning identified 9 signatures including nail pso, CRP and 7 biomarkers to distinguish PsA from PsO pts without arthritis and will help diagnose PsA early. ➡️will need to test independent data @RheumNow #ACR20 Abs#0502

@LCalabreseDO @cappelliMD @MarieKostine @EladSharonMD @rheum_covid For those who missed it, my attempt to capture some of it in a Twitter thread: https://t.co/Z55sV7ZyBt

• https://twitter.com/drdavidliew/status/1324774515386114050

@RheumNow #acr20 abs0063 in silico, in vitro &clinical study: Amitriptyline, naloxone& thalidomide prevent NOS2, IL6, IL1B, MMP9 release, inhibits NLRP3 inflammasome pathway> decreased colchicine consumption in gout pts using above meds for other indications #acrbest #different https://t.co/cz3htmtBU0

#ACR20 keynote Infectious disease Dr Eric Rubin @NEJM EIC answers questions about medications, immunity and vaccines in #COVID19. Many post covid inflammatory symptoms but not sure if its because of background autoimmunity. Need more data. More to come in a few months @RheumNow

Eric Rubin, MD, editor-in-chief @NEJM: "All of the vaccines are based on the same hypothesis". Scary thought in relying in one solution #ACR20. @RheumNow

Lots of JAK safety studies in #ACR20. Abst#0237 pooled 5 RCTs on UPA. Good safety numbers and low VTE rates, but watch out for herpes zoster trend, elevated in UPA (30>15mg) compared to MTX and ADA. @RheumNow

Determining safety of a vaccine requires NUMBERS (more subjects to detect rare, serious side effects) and TIME (longer trials to be able to detect more delayed side effects) per Dr. Eric Rubin’s (ID physician’s) keynote address at #ACR20 @RheumNow