AS/Spondyloarthritis
1 year ago
A possible curative therapy of an autoimmune disease via selective depletion of a TRBV-defined group of T cells. This could be potentially applicable to other HLA-B*27-associated spondyloarthropathies. Year in review, Seo #ACR23 @RheumNow https://t.co/NxxkpJhweH. https://t.co/41Po5CHid3
1 year ago
Smartwatches to measures axSpA activity?
Upadacitinib use in axSpA INCREASED physical activity based on a wearable medical device step count, especially in those who were originally sedentary.
@RheumNow #ACR23 Abs#0530
#ACRbest https://t.co/oOFiQwMFZ6
1 year ago
C-VIEW study on certolizumab use in preventing anterior uveitis in high risk pts with axSpA.
All pts were B27+ w/ at least one episode of anterior uveitis
Uveitis flares lower in certolizumab group compared to non-bDMARD use
@RheumNow #ACR23 Abs#0524 https://t.co/CfnhzStBMv
1 year ago
#CV risk in #AxSpA in Korean population study N=71001, age 42, 71%M but 16% #MTX, 58% #SSZ. #TNFi vs none 30% less CVE. IL17 NO CV reduction but ?confounded by line of #Rx and v large N for TNFi. Study stated PRIOR to IL17i approval #ACR23 @ACRheum @RheumNow L11 poster ?Rx bias https://t.co/3Sft5KUlLa
1 year ago
DESIR cohort update in Abs #0513 shows axSpA pt imaging doesn't "worsen" after pregnancy. However, following 1st pregnancy, can see slight increase in L SIJ score, but typically not enough to define "worsening." #ACR23 https://t.co/HaYj3RQGFb @rheumnow https://t.co/5MQCXS1Kat
1 year ago
Dr. Seo shares an interesting case report on the use of anti-TRBV9 Ab in a patient with AS.
Another potential treatment option for AS?š§
Something to watch out for in the future.
#ACR23 @RheumNow @rheumarhyme https://t.co/y6mQ756TKK
In clinical practice, pulmonary manifestations of rheumatic medical diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), and peripheral spondyloarthritis (pSpA) are typically notā¦
1 year ago
In bDMARD-IR AS patients, UPA led to numerically greater improvements vs PBO in physical activity as measured by a wearable device over 14 wks, especially in sedentary patients. #ACR23 Abs #0530 https://t.co/6Me2XctK6D @rheumnow https://t.co/c6E2GfAGt4
1 year ago
Large Chicago study Abs #0535 at #ACR23 biologic tx prescribed more often for males, Non-Hispanic Blacks and Latinx in AS. Low SES, measured by SDI, and insurance status did not affect if pt received bDMARD. https://t.co/MdDuNPMCC9 @rheumnow https://t.co/Oa9aC3rbb0