Skip to main content

Rheumatoid Arthritis

      #ACRBest https://t.co/nx3bzhmeBW

      Aurelie Najm

      1 year 10 months ago
      There is a dose, duration and recency-dependent relationship between previous GC use and MACE. GC doses 5mg/day, duratio

      Dr. Antoni Chan

      1 year 10 months ago
      There is a dose, duration and recency-dependent relationship between previous GC use and MACE. GC doses 5mg/day, durations of 30 days, and use one year prior to MACE were all associated with an increased risk of MACE, Wallace B Abst#2430 #ACR23 #ACRBest https://t.co/2ExboBvo2W https://t.co/FuqXdFFwqP
      Synovial tissue histology correlates w/ several clinical parameters in early naive RA

      Combination ohigh CD68 infiltrate

      Aurelie Najm

      1 year 10 months ago
      Synovial tissue histology correlates w/ several clinical parameters in early naive RA Combination ohigh CD68 infiltrate Fibrinoid Necrosis in tissue asso w/ -better DA reduction -higher EULAR moderate/good resp Included in a prediction model (AUC0.7) @RheumNow #ACR23 ABST2483 https://t.co/2jCMSzV7ak
      Body mass is associated w/ ttmt response in RA

      Data from RACAT & TEAR studies

      TNFi > triple th in underweight

      Aurelie Najm

      1 year 10 months ago
      Body mass is associated w/ ttmt response in RA Data from RACAT & TEAR studies TNFi > triple th in underweight gpe but not in overweight gpe Similar result in gpe w/ low leptin levels & low adipokine scores True biology or confounding bias? @RheumNow #ACR23 ABST2541 https://t.co/OhKj6QNaSa
      The American College of Rheumatology guidelines for the diagnosis and management of interstitial lung disease, which includes rheumatoid arthritis interstitial lung disease (RA-ILD), has been one of the most controversial topics in the runup to ACR Convergence.
      Who uses #cannabis in #rheumatic #diseases? Those who smoke, have higher pain, more anxiety, poor sleep are more likely

      Janet Pope

      1 year 10 months ago
      Who uses #cannabis in #rheumatic #diseases? Those who smoke, have higher pain, more anxiety, poor sleep are more likely to have used cannabis for their rheumatic disease. Half of the >2900 respondents have tried #cannabis. Use of #biologics reduced use. #980 @RheumNow @ACRheum https://t.co/DQDRQN40zR
      Wouldn’t it be great to be able to predict which women with RA would improve during pregnancy, & which would worse

      David Liew drdavidliew

      1 year 10 months ago
      Wouldn’t it be great to be able to predict which women with RA would improve during pregnancy, & which would worsen? We’d be able to adjust DMARDs accordingly. Gene expression signatures might tell us more - one key cluster here was 21x predictive. #ACR23 ABST2481 @RheumNow https://t.co/OiDV5sUiYC
      Erosive hand #OA may be more painful than treated #RA patients. The burden of OA is often not alked about, and this stud

      Bella Mehta bella_mehta

      1 year 10 months ago
      Erosive hand #OA may be more painful than treated #RA patients. The burden of OA is often not alked about, and this study highlights it! @RheumNow #ACR23 https://t.co/jLbvtMmgE0
      Gene signature predicts RA trajectory during pregnancy:

      Blood RNAseq *before* pregnancy

      🚺 improve during preg: Str

      Aurelie Najm

      1 year 10 months ago
      Gene signature predicts RA trajectory during pregnancy: Blood RNAseq *before* pregnancy 🚺 improve during preg: Strong Neutrophil signature 🚺 experience dis worsening: Strong B cell signature Needs replication but could have major implications! @RheumNow #ACR23 ABST2481 https://t.co/gOHwEvOOM6
      Anti-fibrotics in RA-ILD
      Retro analysis of 74 pts

      AEs frequent 55% and discontinuation in 46% (more than in initial RC

      Aurelie Najm

      1 year 10 months ago
      Anti-fibrotics in RA-ILD Retro analysis of 74 pts AEs frequent 55% and discontinuation in 46% (more than in initial RCTs) No diff between AF FCV trajectory mildly improved ABST2479 @RheumNow @Juge_P_A @PhilippeDieude #ACR23 https://t.co/GqsHxkIFgD
      GCs on MACE in RA in VA
      A#2430 #ACR23 @RheumNow
      Not just ongoing steroid usage, also prior usage 1 year ago
      5 mg use fo

      Eric Dein

      1 year 10 months ago
      GCs on MACE in RA in VA A#2430 #ACR23 @RheumNow Not just ongoing steroid usage, also prior usage 1 year ago 5 mg use for 30 days one year ago - increases MACE events by 3% 5 mg use for 90 days one year ago - increases MACE events by 9%
      Wallace et al. Dose, duration, recency dependent relationship between GC and MACE. Even 5mg/day, 30 day use, and use 1 y

      Richard Conway

      1 year 10 months ago
      Wallace et al. Dose, duration, recency dependent relationship between GC and MACE. Even 5mg/day, 30 day use, and use 1 year prior associated with risk. 5mg, 7.5mg, 10mg pred for 90 days - 13%, 19%, 27% MACE increase Abstr#2430 #ACR23 #ACRbest @RheumNow https://t.co/50B5nGqxu9 https://t.co/lNrUbZOm0o
      Even low doses of steroids associated with major adverse cardiovascular events!

      Large VA database - >18k RA pts
      Dose

      Robert B Chao, MD

      1 year 10 months ago
      Even low doses of steroids associated with major adverse cardiovascular events! Large VA database - >18k RA pts Dose as low as 5mg/day prednisone for 30 days, 1 year prior to event, associated with increased MACE @RheumNow #ACR23 Abs#2430 https://t.co/JjeoBi7YTD
      Lung cancer in RA. @NamrataRheum et al. 26,625 RA HR for lung cancer for b/tsDMARDs vs csDMARDS 1.07 (0.91-1.26) Abstr#0

      Richard Conway

      1 year 10 months ago
      Lung cancer in RA. @NamrataRheum et al. 26,625 RA HR for lung cancer for b/tsDMARDs vs csDMARDS 1.07 (0.91-1.26) Abstr#0453 #ACR23 @RheumNow https://t.co/NLNtyYoaoH https://t.co/tRpt62n62X
      ×