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David Liew drdavidliew
1 year ago
Rheumatologist - pharmacist co-management of MTX initiators @GeisingerHealth Philadelphia
Having the dual skill set actually helped with adherence to guidelines vs standard care. Would be great to see how this works with implementation in RA clinics
#ACR23 ABST2484 @RheumNow https://t.co/88R1BYzYn5
Md Yuzaiful Md Yusof
1 year ago
#ACR23 Abstr# 2490 Data supporting aggressive early treatment in #SLE? Multicentre open label RCT in China showed low dose MMF + Pred 0.5mg/kg/d reduced severe flare & lupus nephritis cases vs HCQ + Pred in new onset SLE with high dsDNA but w/o major organ involvement @RheumNow https://t.co/oRlgCaOvXo
Dr. John Cush RheumNow
1 year ago
Watch: Utility of AI and ChatGPT in Rheumatology
Dr. Kathryn Dao interviews Dr. Richard Stern at the 2023 ACR Convergence meeting in San Diego, CA. #ACR23
https://t.co/SH0TGAdvm8 https://t.co/RHu8bH9YOG
Eric Dein
1 year ago
TM86 #ACR23 @RheumNow
Auricular chondritis, arthritis, axonopathy, high inflamm. Initial Dx: RP
Exam: lymphadenopathy, erythema nodosum, TJC 36, SJC 4 (knees/ankles), decr sensation, asymm reflex, macular rash, nerve thicken
Skin bx: septal panniculitis wo vasc
Dx: leprosy https://t.co/P5QJArRDaA
Janet Pope
1 year ago
#Cardiovascular imaging will help to detect #cardiac abnormalities earlier@in #rheumatic #diseases. #ACR23 @RheumNow @ACRheum 14T118 https://t.co/QKCpLWtkUv
Meral K. El Ramahi, MD MeralElRamahiMD
1 year ago
🚩Adjunct therapy to treat vasculopathy of MDA5-DM
⭐️Botox heals digital ulcerations and improves Raynaud's (slide 1)
Dr. Katherine Shaw injects Botox for healing recalcitrant ulcerated Gottron's papules (example patient failed nifedipine, sildenafil, pentoxyfylline & while on… https://t.co/4XCvRrzeTL https://t.co/yxUCzS30W1
Bella Mehta bella_mehta
1 year ago
What do we know about IL1 drugs in #OA only a small few stidies prior to CANTOS .
COLCHCINE didnt seem to work
LoDoCO2 post hoc analysis may work? @RheumNow #ACR23 https://t.co/h4oVRppI5S
Aurelie Najm
1 year ago
Gene signature predicts RA trajectory during pregnancy:
Blood RNAseq *before* pregnancy
🚺 improve during preg: Strong Neutrophil signature
🚺 experience dis worsening:
Strong B cell signature
Needs replication but could have major implications!
@RheumNow #ACR23 ABST2481 https://t.co/gOHwEvOOM6
Md Yuzaiful Md Yusof
1 year ago
#ACR23 Abstr# 2487 How to reduce PBO response in #SLE trials? Try adding low dose GC as co-primary endpoint. Interim analysis of Phase 2 RCT: SRI-4 + sustained GC dose to ≤5mg/d or ≤BL from Wk16 to 28 was met more in Ianalumab (BAFF-R-i) vs PBO (44% vs 9%) @RheumNow https://t.co/JEnMWKilR6
Eric Dein
1 year ago
TM85 #ACR23 @RheumNow
IPF s/p lung transplant p/w diffuse bone pain
Exam: no synovitis, +crackles. Labs: ALP 203
CT chest: stable mycetoma
Xray: periosteal reaction
Dx: vericonazole periosititis
Positive Mucorales PCR, fluoride level 19 (ref <4)
Bone pain improved stopping voric https://t.co/Gt8mOAssvh
Aurelie Najm
1 year ago
Anti-fibrotics in RA-ILD
Retro analysis of 74 pts
AEs frequent 55% and discontinuation in 46% (more than in initial RCTs)
No diff between AF
FCV trajectory mildly improved
ABST2479 @RheumNow @Juge_P_A @PhilippeDieude #ACR23 https://t.co/GqsHxkIFgD
Meral K. El Ramahi, MD MeralElRamahiMD
1 year ago
Rashes in Rheumatology at #ACR23
Which disease entity are these palms pathognomonic for?
@RheumNow https://t.co/NmT1LTzWmm
Meral K. El Ramahi, MD MeralElRamahiMD
1 year ago
Therapeutic Ladder for Discoid Lupus:
1. Strict🌞protection, smoking avoidance
2. Antimalarials
3. Topicals/intralesional corticosteroids, topical CNI
4. Oral steroids, retinoids, MTX, MMF
5. Thalidomide, lenalidomide
6. IVIG, JAKi, Belimumab... BUT also Anifrolumab!… https://t.co/xSw0s12Uvk https://t.co/stIJ944d9A
Md Yuzaiful Md Yusof
1 year ago
#ACR23 Abstr# 2485 Belimumab therapy in RCT was associated with increased risk of psychiatric events inc suicidality vs PBO. When compared with standard immunosuppressant, real-world data using emulated trial design showed no increased risk @RheumNow https://t.co/Vqhc5yRsSA
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