Daily Recap - WEDNESDAY
Join panelists Drs. Janet Pope, Richard Conway, Meral El Ramahi and Jack Cush recap the best presentations presented on day four of the 2023 ACR Convergence meeting in San Diego, CA.
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What's Hot
EXXELERATE Study: Do High RF Titers Impact Response to TNF Inhibitors?
Dr. Jonathan Kay discusses abstract 2148 with Dr. Josef Smolen at the 2023 ACR Convergence meeting in San Diego, CA.
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Bimekizumab in Active AS: 5 Year Study
Dr. Atul Deodhar reporting on abstract 0519 from the 2023 ACR Convergence meeting in San Diego, CA.
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Cannabinoid Receptor in RA Patients
Dr. Arthur Kavanaugh discusses abstract 0025 at the 2023 ACR Convergence meeting in San Diego, CA.
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Treatments in SpA
Dr. Rachel Tate and Dr. Catherine Blakewell discuss treatment options patients in spondyloarthritis at the 2023 ACR Convergence meeting in San Diego, CA. Abstracts discussed include 0520, 0530, 0521 and 0529.
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PR3+ in Lupus Nephritis
Dr. Jack Cush discusses abstract 2427 presented at the 2023 ACR Convergence meeting in San Diego, CA.
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Simulated Trials to Counter ORAL Survelliance
Dr. Jack Cush and Dr. Janet Pope at the 2023 ACR Convergence meeting in San Diego, CA.
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Difficult to Treat axSpA
Dr. Peter Nash reports on abstracts 0514 and 0538 from the 2023 ACR Convergence meeting in San Diego, CA.
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Window of Opportunity in PsA
Dr. Peter Nash discusses a study that looks at the window of opportunity for treatment of PsA at the 2023 ACR Convergence meeting in San Diego, CA.
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TMP SMX Prophylaxis in GPA
Dr. Jack Cush and Dr. Janet Pope discuss abstract 1584 presented at the 2023 ACR Convergence meeting in San Diego, CA.
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The FOREMOST Study: Apremilast in PsA
Dr. Peter Nash reports on abstract 1691 presented at the 2023 ACR Convergence meeting in San Diego, CA.
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The SMART Study: Split Dose Oral Methotrexate
Dr. Jack Cush discusses abstract 1583 presented at the 2023 ACR Convergence meeting in San Diego.
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Real World Experience with PEXIVAS Low Steroid Taper
Dr. Mike Putman discusses abstract 0725 with Dr. Sophie Nagle at the 2023 ACR Convergence meeting in San Diego, CA.
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Cancer and TNF inhibitors
Cancer risk minimisation is a high priority for people with rheumatic diseases, as it is for the general population. Tumor necrosis factor inhibitors (TNFi) have a long history of association with cancer risk discussions. An oral presentation by Suarez-Almazor et al provided more supportive data on using TNFi in this population.
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#ACRbest Abstracts – Day 2
Our reporters have been prolific in finding the hot abstracts, those that were most attended or those that are getting the most buzz on social media. Here are RheumNow's #ACRbest abstract reports from Monday, November 13, 2023 at #ACR23, covering The Great Debate, SGLPT2 inhibitors in SLE, the SMART Study of MTX, TMP/SMX Prophylaxis, RA-ILD & TNF Inhibitors, cancer research and more.
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Effects of Apremilast on Cardiometabolic Effects in PsA
Dr. Peter Nash discusses abstract 1414 at the 2023 ACR Convergence meeting in San Diego, CA.
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An Interview with Kevin Winthrop: Three Questions About COVID 19
Drs. Jack Cush and Kevin Winthrop discuss COVID 19 at 2023 ACR Convergence in San Diego, CA.
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Biologics as First-line Therapy for PMR and GCA?
Dr. Eric Dein talks with Dr. Philip Seo, one of two panelists for the Great Debate: Should PMR and GCA Be Treated with Advanced Therapies at Disease Onset? at the 2023 ACR Convergence meeting in San Diego, CA.
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Dr. Rachel Tate
2 years ago
Where does CAR-T fit in the future landscape? Dr. Seo reviews two case studies that question additional questions regarding efficacy, longevity of efficacy, and additional questions necessary to answer for our patients. #ACR23 @RheumNow https://t.co/mi4Z1tuJIV
TheDaoIndex KDAO2011
2 years ago
Half a pizza > once a week might help RA! Type of pizza matters as it is the ingredients- fresh mozzarella, olive oil are main ingredients #NotDominoes #YearinReview @RheumNow #acr23 https://t.co/i86JtUhXwW
Aurelie Najm
2 years ago
#ACR23 #ACRpearls
Breaking news: Pizza 🍕 DOES improve disease activity in RA
Eating half a pizza > 1 time a week reduces SDAI -3.6
Dr Philip Seo warns us though, authors emphasizes it only applies to the ‘REAL’ Italian pizza👌🏻
#yearinreview
@RheumNow https://t.co/xt7uEYFoW1
TheDaoIndex KDAO2011
2 years ago
It’s surprising (or not) there are common gene signatures in different autoimmune dz #YearInReview #ACr23 @RheumNow https://t.co/Jx52dsp6L2
TheDaoIndex KDAO2011
2 years ago
Checkpoint inhibitor assc arthritis may be assc with a particular clonal T cell that produce type I IFN. #YearInReview #ACR23 @RheumNow https://t.co/CEB0lCkzls
Dr. Rachel Tate
2 years ago
Dr. Seo sells the benefits of pizza consumption in RA at #ACR23 YiR. This Italian study followed adult RA pts who ate half a pizza (Italian sized!) > 1 x/week self reported improvement in their disease! Personally, I can assure that mozzarella and olive oil significantly improve… https://t.co/zLocmDu4Z4 https://t.co/WkCZHteL8O
TheDaoIndex KDAO2011
2 years ago
Maintenance regimen for #AAV- AZP and On demand RTX inferior to RTX q6 months. Scheduled RTX for 18 or 36 months is better and results the same. AES similar in all group #ACR23 @RheumNow #YearinReview https://t.co/SpA9mY6syZ
Mike Putman EBRheum
2 years ago
Slides (vexingly) unavailable for ILD guideline talk, thanks @DrPujaMehta1 for the quick snap!
As expected, ILD guidelines "suggestion" for who to screen is "way way more than before"
My thoughts in full:
https://t.co/QC7ZLxjdJk
@RheumNow #ACR23 https://t.co/BuhJFgpfZh
Robert B Chao, MD
2 years ago
What are you using for ANCA vasculitis maintenance?
Not much difference in AZA vs. RTX on demand
70% relapse free in RTX q6 month for 18 months
NO difference in similar 36 month group
Should maintenance w/ RTX only last for 18 months?
Food for thought
@RheumNow #ACRbest https://t.co/zNdIEODpeS
Dr. John Cush RheumNow
2 years ago
NEJM: Clinical Examination of the Cervical Spine (full read, with video). Great overview of Cx exam, useful in evaluation of axial neck pain, radiculopathy, or myelopathy; info on dermatomes, reflexes, Lhermites sign, etc https://t.co/QYD1ZahqTS https://t.co/K0XhlHYXoz
TheDaoIndex KDAO2011
2 years ago
Novel approach to ank spond. Case report. #YearinReview #ACR23 @RheumNow https://t.co/fWb1qdEcOS
Robert B Chao, MD
2 years ago
Very cool targeted T cell ab treatment against TRBV9+ T cells provided remission in ankylosing spondylitis!
Albeit only case report
However Phase 2 ongoing
@RheumNow #ACR23 https://t.co/pm64QeTo1U
Mike Putman EBRheum
2 years ago
Brilliant summary slide re:RA and PsA during an as-always entertaiing by Dr. Seo
Personal opinion?
-Persolimab will have narrow role & may cause CA
-BIME will be 2nd line for PsA
-Tyk-2's will be the next big thing
Also... time for H2H trials!!!
@RheumNow #ACR23 https://t.co/lDvsK8h7WH
Dr. Rachel Tate
2 years ago
#ACR23 YiR! Dr. P. Seo reviews 2023 novel therapeutic agents we may see on the horizon. @RheumNow https://t.co/d0V41jAh3G
Poster Hall