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Rheumatoid Arthritis

      T cells are known to play a key role in RA pathogenesis and the diversity of the T cell repertoire is known to be reduced in RA.  In POS0009, Anang et al. studied T-cell receptor repertoire (…
      RT @bella_mehta: Abstracts talking about #RA and JAKs and Biologic comparisons
      Huge number of pts to analyze this aftrr
      1 year 5 months ago
      Abstracts talking about #RA and JAKs and Biologic comparisons Huge number of pts to analyze this aftrr the initial NEJM study. Abstract summary pics below @RheumNow https://t.co/jl5S4fLq19
      RT @bella_mehta: Abatacept in pts at risk of #RA data from clinical trial.
      213 pts, 31 centers.
      Pts with multiple autoa
      1 year 5 months ago
      Abatacept in pts at risk of #RA data from clinical trial. 213 pts, 31 centers. Pts with multiple autoantibodies improved the most with abatacept. @rheumnow #EULAR2023 https://t.co/c82jx0cAEq
      RT @AurelieRheumo: Treat early it is also cheaper!

      5 yr cost of RA ttmt

      €11250 ACPA+ > €3526 ACPA-

      bDMARDS us
      1 year 5 months ago
      Treat early it is also cheaper! 5 yr cost of RA ttmt €11250 ACPA+ > €3526 ACPA- bDMARDS users €44788 ACPA+ > €40896 ACPA- ACPA- "late" ttmt 46% more expensive ACPA+ early vs. late = similar costs @Rheumnow #EULAR23 POS0369 https://t.co/dg9T9fqJDl
      RT @Janetbirdope: In ERA high BMI is associated with high BMI is assoc with failure to get to Low disease activity. From
      1 year 5 months ago
      In ERA high BMI is associated with high BMI is assoc with failure to get to Low disease activity. From NORD-STAR RCT. Cdn CATCH cohort in #early #Rheumatoid #arthritis also shows I is associated w less remission and less sustained remission #EULAR2023 @RheumNow POS0324 https://t.co/9EXY8Dyz74
      RT @Janetbirdope: Predictive model to predict RA status via AI , to know what goes in to model or predictions may change
      1 year 5 months ago
      Predictive model to predict RA status via AI , to know what goes in to model or predictions may change. Ex use of DMARDs https://t.co/fkcEKfZWl8
      RT @AurelieRheumo: We would think that targeted therapies would have reduced GC use in RA.

      Well, this is not really the
      1 year 5 months ago
      We would think that targeted therapies would have reduced GC use in RA. Well, this is not really the case. Comaprison of GC use in 1999-2008 vs. 2009-2018 52% of patients remain on GC for>3Mo after initiation & 1/3 still continues after 2 years! @RheumNow #EULAR23 POS0309 https://t.co/dDkUJFlmEm
      RT @Janetbirdope: What is the course of clinically suspect arthralgia in CCP+ vs neg? 781 pts, 136 got RA and sl more re
      1 year 5 months ago
      What is the course of clinically suspect arthralgia in CCP+ vs neg? 781 pts, 136 got RA and sl more resolved symptoms. RA developed in both groups ACPA+ develop more rapidly - if resolution, still more MRI + vs neg. #EULAR2023 POS319 @RheumNow Diff patterns of progression