A#1403 #ACR23 @RheumNow 17% of 1st degree relatives of AS pts have MRI-defined sacroiliitis Study of 100 subjects w FHx AS - 13/100: new dx of AxSpA, 7 w radiographic changes - 4/100: Sacroiliitis without back pain - 1 periph SpA - 12 met clinical ASAS classification but not dx https://t.co/V7LCbaDXBe

17% of 1st degree relatives AS pts had MRI- defined sacroiliitis, however not all of them were diagnosed w/ SpA due to absence of back pain. 25% w/ 1st degree AS relative met the classification criteria for SpA #ACR23 Abs #1403 https://t.co/W1T9ZqD4o1 @rheumnow https://t.co/DnaNSLiqfU

Does NSAID use = CKD? Large Korean study on CKD in ankylosing spondylitis pts showed risk of CKD associated with comorbidities. Long term NSAID use not associated with increased risk of CKD. @RheumNow #ACR23 Abs#1394 https://t.co/m3kYI30gBc

Risk of CKD in AS patients was associated with comorbidities, not NSAID use. #ACR23 Abs #1394 https://t.co/cbOPvjOCyq @rheumnow https://t.co/O0rhbMFiOX

Majority of pts with axSpA had below avg aerobic capacity indicating high risk of morbidity. Importance of supporting pts with axSpA to lead healthy lifestyle and improved aerobic capacity by exercise! @RheumNow #ACR23 Abs#1395 https://t.co/SFAStGQaK0

What if you have a first degree relative with ankylosing spondylitis? 100 pts w/o previous rheum dx w/ 1st degree AS relative 17% had MRI sacroiliitis 25% met classification criteria 14% dx with AS @RheumNow #ACR23 Abs#1403 https://t.co/Z0juhRnLki

15-year results from Abs #1389 at #ACR23 found only low back pain to be predictor of spinal radiographic progression in axSpA pts. Mean and median progression changes by mSASSS per year less in this cohort than previously documented. https://t.co/VKTEZWvH7f @rheumnow https://t.co/6sjPrcw2dD

Biologics are working for ankylosing spondylitis, even in reducing cardiovascular mortality! Large retrospective study of over 4k pts over 20 years showed decrease in CV mortality from 34% in 1999 to 21% in 2020 @RheumNow #ACR23 Abs#1399 #ACRbest https://t.co/wKCIXHza0v