Hand movement video: more promising than photos as a computer vision concept for remote monitoring of RA disease activity. Of course: validation, training, clinical evaluation all must happen before it is ready for your clinic https://t.co/HyN6ElKF0F #ACR23 ABST1293 @RheumNow https://t.co/DltI9HFiFE

Fatigue 😴 in RA & synovial biology In DAS LDA pts Fatigue asso w/ -female sex -synovial lymphocytic inflammation In DAS moderate DA: -female sex -synovial lining layer -Anxiety Limitations: arthroplasty tissue, small sample size, no Immunohisto @RheumNow #ACR23 ABST1630 https://t.co/4vhzvdPgyd

Fisher et al. In high disease activity, fatigue associates anxiety and synovial lining hyperplasia, 1.57[1.01,2.5]; p=0.047) In LDA, fatigue associates chronic lymphocytic synovial inflammation, 1.92[1.09,3.57]; p=0.024) Abstr#1630 #ACR23 @RheumNow https://t.co/Gev6pU3srq https://t.co/Ys8etP36ir

Do we miss RA activity in obese pts? Pre-clinical trial entry MSK USS: similar DAS28 but lower SJC/US scores in obese Is it because, in obese RA patients: we underdetect on exam? we undertreat? higher risk, so lower penetrance of severe dx endotypes? #ACR23 ABST1287 @RheumNow https://t.co/3FFPdBJOpz

Multimorbidity in #RA - VARA registry data- looking at 61 different biomarkers and 44 comorbidities Chronic pain in 44% Specific biomarkers seen in different morbidities @rheumnow #ACR23 session#13M148 https://t.co/l6FU1ELKD3

Peyton et al.: 4 multimorbidity patterns in RA -Mental health and subst abuse -Metabolic -CV -Chronic pain All associated with different sets of biomarkers. Some are very specific of one profile while others are widespread across profiles. @RheumNow #ACR23 ABST1631 https://t.co/VqCrLI3oyy

In PS-matched study, no significant difference in respiratory hospitalisation or death between RA-ILD patients on non-TNFi/JAKi vs. TNFi. This finding does not support systematic avoidance of TNFi in RA-ILD, England B Abst#1582 #ACR23 #ACRBest @RheumNow https://t.co/1zVjMWNZZS https://t.co/d8TRIvGaIe

Abst#1583 SMART study: Split dose qwk MTX (10 mg QAM, 15 mg QPM) may have better efficacy compared to 25 mg single dose qwk MTX. RCT 253 RA patients: split dose had better DAS score, less likely to add other DMARDS, but slight⬆️in LFTs. #Plenary #ACR23 @rheumnow #ACRbest

It's OK to use TNFi in RA-ILD! VA study 1000+ pts using Target Trial Emulation framework: TNFi vs nonTNFi biologics/JAKi followed for 3 years. NO differences in respiratory hospitalizations or deaths or all cause mortality. abst#1582 #ACR23 #ACRbest @rheumnow https://t.co/aI2SmMrLPE