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Eric Dein
1 year ago
ARTIC REWIND: To taper or not?
A#L07 #ACR23 @RheumNow
RA pts taper TNFi in stable remission
No taper group: 85% flare free in 3 yrs
Taper grp: only 25%
Lower Boolean 2.0 Remission rates
Don't taper off a good thing! https://t.co/KnJrEfVFkV
Janet Pope
1 year ago
Lessons for #CVD in #inflammatory #rheumatic #diseases #ACR23 @RheumNow @ACRheum #ACRbest
-Negative #coronary #calcification doesn’t r/o presence of #microvascular #dysfunction
- work w #cardiologist for@proper@imaging for #Dx
-for #CAD or #pericarditis #Colchicine is GOOD https://t.co/dMO1FpoA2a
Janet Pope
1 year ago
Excellent session: Navigating CV risk for #inflammatory #arthritis - view from #cardiology #ACR23 14T118 @RheumNow @ACRheum https://t.co/WKhh0TonE8
Md Yuzaiful Md Yusof
1 year ago
#ACR23 Late-Breaking Abstr#L14 Which team are you on? IL5-i or IL5-receptor-i #EGPA. Phase 3 H2H RCT showed similar efficacy btw Mepolizumab and Benralizumab, with more pts fully tapering off GC at WK52 favouring BENRA. Rapid reduction in Eosinophils too @RheumNow #ACRBest https://t.co/cXhSS80mA2
Janet Pope
1 year ago
Is #cardiology now a specialty like #rheumatology with bDMARDs? Many pathways discussed for CVD in #rheumatoid #arthritis. And biologics for lowering lipids too! #ACR23 @ACRheum @RheumNow 14T118. More overlap of pts over time! https://t.co/blv5GmHTGe
Eric Dein
1 year ago
A#L06 #ACR23 @RheumNow
Refractory juv SSc 6m-2y after autolog Stem Cell Tx - 5 patients
HAQ VAS improved 75% (48-99%)
All: mRSS MCID by 6 mo, 87% aver improvement, sustained at 2y
GI: GIT mean 55% improvement, 1 unchanged
FVC stable, DLCO improv >10% in 2, 5-10% in 2
#ACRBest https://t.co/cc6YToVEO5
Janet Pope
1 year ago
#Cardiology imaging has advanced - work with #cardiologists to know what to order - esp for our Pts w #inflammatory #diseases #ACR23 @RheumNow @ACRheum 14T118 https://t.co/RuHJuy7Dh2
Adela Castro AdelaCastro222
1 year ago
Speaking of influencing in rheumatology… @RheumNow and @anisha_dua know best! #ACR23 #Facesofrheumatology https://t.co/EsppP3FPoX
Eric Dein
1 year ago
MANDARA: Benralizumab v Mepolizumab in EGPA
A#L14 #ACR23 @RheumNow
P3, 52w RCT, 140 pts
Remission rate: 59% Ben, 56.5% Mep
Relapse rate 30% in both
86% Ben, 74% Mep had reduction of GC dose 50%+, 41% v 26% tapered off
SAEs: 6% Ben, 13% Mep
Concl: Non-inferiority of Ben v Mep https://t.co/mSIFsDq8eL
Mike Putman EBRheum
1 year ago
I continue to be underwhelmed by nintedanib, esp in RA-ILD
Data from INBUILD-ON, f/u study to the INBUILD basket trial
Persistent loss of FVC... wonder how pts would have done had they received an RA-active DMARD?
Need H2H vs TNFs & real DMARDs
@RheumNow #ACR23 Abstr 2158 https://t.co/56PgC6Uc67
Dr. John Cush RheumNow
1 year ago
Real-World Issues in AxSpA: Treatment Intensification, Pregnancy
Dr. Rabab Nezam El-Din and colleagues explored patient- and disease-related determinants that were associated with treatment intensification among axSpA patients w/ high disease activity.
https://t.co/vZ66hsErBI https://t.co/pN8JZAEcqv
Richard Conway
1 year ago
MANDARA phase 3 RCT Benralizumab vs Mepolizumab in relapsing/refractory EGPA receiving SOC. Non-inferiority met. Abstr#L14 #ACR23 @RheumNow https://t.co/UnpF3RDHMa https://t.co/076SeynJx3
Dr. Rachel Tate
1 year ago
Prelim data supports further evaluation of YTB323 in srSLE. #ACR23 Abs L13 reviews safety, CAR-T cell expansion, B cell depletion and initial efficacy in 1st 3 pts. https://t.co/aOLMhBBjgY @rheumnow https://t.co/2BoNeMe3Tg
Richard Conway
1 year ago
Phase 2 RCT. Selective JAK1i LNK01001 in RA. 156 patients, 24 week (12 week PBO controlled). Abstr#L09 #ACR23 @RheumNow https://t.co/hHjL1yFH0H https://t.co/Qls4zRrRGH
Dr. John Cush RheumNow
1 year ago
RheumNow’s expanded coverage of the #ACR23 annual meeting is sponsored in part by Novartis. All content is chosen by RheumNow & its faculty.
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