Anti-Rheumatic Rx
1 year ago
#ACR23 Abstr#2576 Promising therapy in Dermatomyositis. Phase 2 RCT showed rapid improvement in skin, muscle & patient reported outcomes as fast as Week 4 in PF-06823859 (anti-IFN-B) vs PBO. Could be useful to treat in either skin or muscle predominant patients @RheumNow #ACRBest https://t.co/Rj1k1z0Tsz
1 year ago
L20 @ #ACR23
New therapy on the horizon for RA pts that failed MTX?
⭐️Telitacicept = recombinant fusion protein targeting & neutralizing BLyS & APRIL
➡️ placebo-controlled, phase III trial, 24w
👉at wk 24, PBO pts switched to drug arm for 24 more wks
➡️ 479 pts w/… https://t.co/94MyC8sdaG https://t.co/x3MUmFJPK6
1 year ago
What happens when you stop #steroids and/ immunosuppressive Rx in Pts in remission for at least 1 yr in #IgG4 disease?
You are likely guessing correctly
Pts flare! Don’t stop Rx
?taper 🤷♀️
Like RA Rx - if stop Rx = flares
Large RCT from China L16 #ACR23 @RheumNow @RheumNow
1 year ago
#IA Injection in #knee #OA.
TLC599 vs #dexamethasone vs saline #RCT-blinded.
Both active #Rx better than #PBO. Some differences in average daily pain between active drugs.
Not sure where it may fit in? After IA steroid failure?
L18 #ACR23 @ACRheum @RheumNow https://t.co/rLh6ISBpUw
1 year ago
#ACR23 Abstr#2578 AI to phenotype sporadic IBM vs AI Myositis
-Anti-NT5c1A assoc with dysphagia
-Anti-Ro52/TRIM21: female
-Anti-VCP: male
-Anti-NT5c1A + clinical markers: high accuracy in separating SIBM vs AIM
Need longitudinal data for clusters to be meaningful @RheumNow https://t.co/fu0a074XAZ
1 year ago
#ACR23 BEST Abstracts from San Diego – Day 1
From hundreds of online presentations, the poster floor and the plenary podium, here are some of the best abstracts from 11/12/23. You can spot these on Twitter by looking for the (#ACRbest) hashtag.
https://t.co/h4RvFy66z9 https://t.co/LEhAUaw6Cj
These year’s annual ACR Convergence has been a success with the return of an insanely active Poster Hall! F2F learning amidst miles of research and many young talented aside wizened establish…
For as long as I can remember, methotrexate has been the anchor drug treatment of rheumatoid arthritis. It is one of the most widely used drugs in rheumatology, even outside of rheumatology. We also…