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Spondyloarthritis

      ACR QD Clinics - Neighbor Consults
      Study of TNFi tapering in 108 axSpA patients in remission. Gradual tapering over 2 yrs resulted in flares in 99% (108).

      Dr. John Cush RheumNow

      1 year 11 months ago
      Study of TNFi tapering in 108 axSpA patients in remission. Gradual tapering over 2 yrs resulted in flares in 99% (108). - 27% flared at 2/3 dose - 20% at 1/2 dose - 27% at 1/3 dose - 25% w/ discontinuation WHY WOULD YOU DO THIS? I DONT! https://t.co/g8L7E4lcqG https://t.co/oaBILUrlmd
      Dr. Jack Cush reviews the news, journal reports and regulatory approvals from the past week on RheumNow.com. Study of LATE-onset RA (>65y), shows DMARD initiation is low in LORA;  despite current clinical practice guidelines recommending early aggressive Rx. Among 3,373 LORA pts (age77 yrs),  only 29% initiated on a DMARD. https://bit.ly/47dT6x6
      JAK inhibitors are known to increase the risk of herpes zoster infections between between 3-5 fold.  Two recent reports suggest variable efficacy when JAK inhibitor (JAKi) treated patients are vaccinated with the recombinant herpes zoster subunit vaccine (RZV). 
      RheumNow Live registration is NOW OPEN! Early bird pricing through 11/30/2023. Register today!

      https://t.co/1SjBiM7Daj

      Dr. John Cush RheumNow

      1 year 11 months ago
      RheumNow Live registration is NOW OPEN! Early bird pricing through 11/30/2023. Register today! https://t.co/1SjBiM7Daj https://t.co/w2cFcj85r5
      RheumNow Live registration is NOW OPEN! Early bird pricing through 11/30/2023. Register today!

      https://t.co/7OsdPYWukv

      Dr. John Cush RheumNow

      1 year 11 months ago
      RheumNow Live registration is NOW OPEN! Early bird pricing through 11/30/2023. Register today! https://t.co/7OsdPYWukv https://t.co/QoCxR04bJD
      Sleep problems in SpA & PsA? Study of 201 pts shows 43% of axSpA and 47% of PsA pts reported sleep problems. In bo

      Dr. John Cush RheumNow

      2 years ago
      Sleep problems in SpA & PsA? Study of 201 pts shows 43% of axSpA and 47% of PsA pts reported sleep problems. In both poor sleep assoc w/ dz activity. In axSpa it signif assoc w/ Dz activity (OR 8.45),biologic use (OR .24), & CRP levels (OR .16) https://t.co/7juI2Dghjh https://t.co/SxCaJgTmeQ
      Dr. Jack Cush discusses the news, journal articles and regulatory actions. This week we discuss JAKne, DLE and SLE and more.
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