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      Ab2674 #ACR24
      ➡️Most pts starting 1st-line TNFi, who didn't achieve treatment response at 3M, also didn't achieve re

      Mrinalini Dey DrMiniDey

      1 month ago
      Ab2674 #ACR24 ➡️Most pts starting 1st-line TNFi, who didn't achieve treatment response at 3M, also didn't achieve response from months 3-12 ➡️1/4 pts achieving LDA/remission at 3M were no longer in LDA/remission at 12M @RheumNow https://t.co/pFOo86tJTx
      Data from the RISE registry show that 9.3% of SLE pts had thrombocytopenia and a smaller percentage with mod-severe TP (

      sheila RHEUMarampa

      1 month ago
      Data from the RISE registry show that 9.3% of SLE pts had thrombocytopenia and a smaller percentage with mod-severe TP (2.7%). Severe TP was much rare. Large data, but well represented grp? @RheumNow #ACR24 abs2680 https://t.co/Y1Lo9lJGtO
      An early favorable response to TNFi initiation indicates better long-term success in RA. Assess early and adjust treatme

      Jiha Lee JihaRheum

      1 month ago
      An early favorable response to TNFi initiation indicates better long-term success in RA. Assess early and adjust treatment accordingly. #ACR24 @RheumNow ABST#2674 https://t.co/YTThYiiLpZ
      #ACR24 BEST Abstracts from Day 1

      The RheumNow faculty have parked at the plenaries, trafficked the posters and have bee

      Dr. John Cush RheumNow

      1 month ago
      #ACR24 BEST Abstracts from Day 1 The RheumNow faculty have parked at the plenaries, trafficked the posters and have been finding the best the meeting offers on the first day. https://t.co/FHu616Jpyq https://t.co/oKuRcGRRAZ
      Would you trust #AI to carry out & read your #USS?

      2 systems, ARTHUR & DIANA, were comparable to that of a rheu

      Mrinalini Dey DrMiniDey

      1 month ago
      Would you trust #AI to carry out & read your #USS? 2 systems, ARTHUR & DIANA, were comparable to that of a rheumatologist specialising in MSK US at joint & patient levels Might this be the future of assessment in rheumatology care? AbL20 #ACR24 @RheumNow https://t.co/XtnlYafzp4
      Nailfold video capillaroscopy (NVC) allows the definite distinction between primary and secondary #Raynaud's phenomenon

      sheila RHEUMarampa

      1 month ago
      Nailfold video capillaroscopy (NVC) allows the definite distinction between primary and secondary #Raynaud's phenomenon and can identify early changes such as few giant capillaries &/or microhemorrages promoting early diagnosis @RheumNow #ACR24 @rheumarhyme https://t.co/Yl37w6BEZR
      Another + #SLE #RCT - large N

      #Dapirolizumab = Peg CD40L + SoC
      Vs
      #Placebo + SoC

      Rapid improvemt
      steroid sparing

      S

      Janet Pope Janetbirdope

      1 month ago
      Another + #SLE #RCT - large N #Dapirolizumab = Peg CD40L + SoC Vs #Placebo + SoC Rapid improvemt steroid sparing So what to use in Pts if +Ph3 👇 TYK2 Deucravacitinib JAKi Upadacitinib Dapirolizumab CAR 🚗 Rx Anifrolimumab Benlysta ETC! #ACRBest L16 @RheumNow #ACR24 https://t.co/wTFucF7BYO
      Late breaking abstract L17
      CAR-NK Therapy for Refractory SLE.
      In a trial of 20 severe SLE patients:
      - 75% achieved LLDAS

      Antoni Chan MD (Prof) synovialjoints

      1 month ago
      Late breaking abstract L17 CAR-NK Therapy for Refractory SLE. In a trial of 20 severe SLE patients: - 75% achieved LLDAS, 50% achieved DORIS remission at 6 months - B cell reconstitution: 2–3 months post-treatment - Safety: 2 mild cytokine release syndrome with fever; no severe… https://t.co/MS8cutm48o
      The combe-like pattern is observed in pts with APS and also in overlap syndrome
      - presence of parallel microthrombi (ora

      sheila RHEUMarampa

      1 month ago
      The combe-like pattern is observed in pts with APS and also in overlap syndrome - presence of parallel microthrombi (orange arrow) arranged perpendicularly, hence combe-like @RheumNow #ACR24 @rheumarhyme https://t.co/IjX7ld9lxW
      The #scleroderma-like pattern on NVC is observed in pts with #dermatomyositis and MCTD
      It consists of a combination of g

      sheila RHEUMarampa

      1 month ago
      The #scleroderma-like pattern on NVC is observed in pts with #dermatomyositis and MCTD It consists of a combination of giant capillaries, some microhemorrhages, severe capillary loss and angiogenesis @RheumNow #ACR24 @rheumarhyme https://t.co/WO9BOYn4ir
      In Vivo CAR T Cell Therapy.
      A single intralymphatic injection of VivoVec™ particles:
      - Generates functional CAR T cell

      Antoni Chan MD (Prof) synovialjoints

      1 month ago
      In Vivo CAR T Cell Therapy. A single intralymphatic injection of VivoVec™ particles: - Generates functional CAR T cells in vivo - Achieves complete B cell depletion in NHPs without lymphodepletion - Demonstrates potential for an off-the-shelf solution for autoimmune disease… https://t.co/5DTzRvZjbY https://t.co/DvTOqnhn1V
      Wt ⬇️ = Better #PROs in

      👇autoimmune #rheumatic #diseases if > 5% wt loss.

      #ACR24 ⁦@ACRheum⁩ ⁦@RheumN

      Janet Pope Janetbirdope

      1 month ago
      Wt ⬇️ = Better #PROs in 👇autoimmune #rheumatic #diseases if > 5% wt loss. #ACR24 ⁦@ACRheum⁩ ⁦@RheumNow⁩ Didn’t work for non overwt Ex Normal BMI and T2DM 🤷 https://t.co/81OuTfZ0Nx
      🚨 New SLE treatment update! 🚨 Dapirolizumab pegol (DZP), novel CD40L inhibitor, for moderate-to-severe lupus. Phas

      Bella Mehta bella_mehta

      1 month ago
      🚨 New SLE treatment update! 🚨 Dapirolizumab pegol (DZP), novel CD40L inhibitor, for moderate-to-severe lupus. Phase 3 trial, DZP reduced disease activity, helped taper steroids, and achieved a higher BICLA Safe and generally well tolerated! #ACR24 #L16 @rheumnow https://t.co/lFrKjz4CZ1
      In this study by Dr CArriens et al, there was no difference between the vaccine response to Influenza by either HAI or A

      sheila RHEUMarampa

      1 month ago
      In this study by Dr CArriens et al, there was no difference between the vaccine response to Influenza by either HAI or Ab levels in Anifrolumab-treated pts. AEs - mild, moderate No serious aEs 💉#vaccinate your pts on anifrolumab with influenza @RheumNow #ACR24 abs2424 https://t.co/XPwlzUS02i
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