Lupus
2 years 5 months ago
Teng et al BLISS-BELIEVE Biomarker outcome RCT Sequential belimumab-rituximab in SLE. Certainly appears to be a serologic benefit on dsDNA, C3/4. But we need clinical parameters to correlate with this. @RheumNow #EULAR2022 OP0281 https://t.co/iEeSN0SNcr https://t.co/HN8ya4QZLU
2 years 5 months ago
Manzi et al. Data on anifrolumab from TULIP studies on depression/suicidality. No effect. @RheumNow #EULAR2022 OP0282 https://t.co/5n7HBqzLkX https://t.co/fq4dxskJaA
2 years 5 months ago
#POS0757 #EULAR2022 What is the perception of #lupus patients on #COVID19 recovery? A survey of 202 pts from BILAG-BR (N=20 case+, 3 hospitalised) reported full recovery from covid in only 1/3 of patients. These pts would need extra support @RheumNow https://t.co/SdH223Lfoa
2 years 5 months ago
Schett et al. CAR-T in SLE, case series 4 patients. Effective in inducing clinical remission in all 4 refractory patients. Looks like #rheummadness may have been (almost) correct @DavidLeverenz ! @RheumNow #EULAR2022 OP0279 https://t.co/frAU8COFs8
2 years 5 months ago
More data on #iberdomide… from phase 2 study --looks like it helps #SCLE and #CCLE (but not for #ACLE) Dr. V Werth #EULAR2022 @rheumnow https://t.co/FYZlB219lf
2 years 5 months ago
Potential new target anti-BDCA2 Ab, #litifilimab targets pDC… impressive phase 2 studies with sig improvement in CLASI-A scores #EULAR2022 @rheumnow https://t.co/hJGx3c3Fbb
2 years 5 months ago
#PEARLS by Dr. Werth:
1. anti-malarials only work 50% of time for cutaneous lupus (CLE).
2. AZP is not as effective as MTX or MMF for #CLE
3. Consider RTX refractory #bullous lupus #EULAR2022 @rheumnow https://t.co/6FPJEGWioJ
2 years 5 months ago
Hilarious debate #EULAR2022 between Christian Dejaco and Robert Landewe on whether telemedicine is the future of rheumatology. In amongst the trash talking, here are some highlights @RheumNow
2 years 5 months ago
#PEARLS by EULAR President Prof Iagnocco:
1. Enthesitis can be present in 25% of #SLE patients
2. Erosions can be common and independent of ACPA/RF status
3. Active myositis is indistinguishable from IIM
4. Don't forget pain osteonecrosis/osteomyelitis #EULAR2022 @rheumnow https://t.co/8uWCw9rEve
2 years 5 months ago
Staggering facts by Prof Vital on #SLE and SkM Sx’s:
- 50% of first Sx’s is SkM
- SkM Sx are in top 3 concerns for pts
- 34% pts w/SkM Sx stopped working median 4 yrs
- SkM damage clusters with CVD damage
#EULAR2022 @rheumnow https://t.co/NXEW3XYCQZ