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Rheumatoid Arthritis

      There is a dose, duration and recency-dependent relationship between previous GC use and MACE. GC doses 5mg/day, duratio
      1 year ago
      There is a dose, duration and recency-dependent relationship between previous GC use and MACE. GC doses 5mg/day, durations of 30 days, and use one year prior to MACE were all associated with an increased risk of MACE, Wallace B Abst#2430 #ACR23 #ACRBest https://t.co/2ExboBvo2W https://t.co/FuqXdFFwqP
      Synovial tissue histology correlates w/ several clinical parameters in early naive RA

      Combination ohigh CD68 infiltrate
      1 year ago
      Synovial tissue histology correlates w/ several clinical parameters in early naive RA Combination ohigh CD68 infiltrate Fibrinoid Necrosis in tissue asso w/ -better DA reduction -higher EULAR moderate/good resp Included in a prediction model (AUC0.7) @RheumNow #ACR23 ABST2483 https://t.co/2jCMSzV7ak
      Body mass is associated w/ ttmt response in RA

      Data from RACAT & TEAR studies

      TNFi > triple th in underweight
      1 year ago
      Body mass is associated w/ ttmt response in RA Data from RACAT & TEAR studies TNFi > triple th in underweight gpe but not in overweight gpe Similar result in gpe w/ low leptin levels & low adipokine scores True biology or confounding bias? @RheumNow #ACR23 ABST2541 https://t.co/OhKj6QNaSa
      The American College of Rheumatology (ACR) guidelines for the diagnosis and management of interstitial lung disease, which includes rheumatoid arthritis interstitial lung disease (RA-ILD), has been…
      Who uses #cannabis in #rheumatic #diseases? Those who smoke, have higher pain, more anxiety, poor sleep are more likely
      1 year ago
      Who uses #cannabis in #rheumatic #diseases? Those who smoke, have higher pain, more anxiety, poor sleep are more likely to have used cannabis for their rheumatic disease. Half of the >2900 respondents have tried #cannabis. Use of #biologics reduced use. #980 @RheumNow @ACRheum https://t.co/DQDRQN40zR
      Wouldn’t it be great to be able to predict which women with RA would improve during pregnancy, & which would worse
      1 year ago
      Wouldn’t it be great to be able to predict which women with RA would improve during pregnancy, & which would worsen? We’d be able to adjust DMARDs accordingly. Gene expression signatures might tell us more - one key cluster here was 21x predictive. #ACR23 ABST2481 @RheumNow https://t.co/OiDV5sUiYC
      Erosive hand #OA may be more painful than treated #RA patients. The burden of OA is often not alked about, and this stud
      Erosive hand #OA may be more painful than treated #RA patients. The burden of OA is often not alked about, and this study highlights it! @RheumNow #ACR23 https://t.co/jLbvtMmgE0
      Gene signature predicts RA trajectory during pregnancy:

      Blood RNAseq *before* pregnancy

      🚺 improve during preg: Str
      1 year ago
      Gene signature predicts RA trajectory during pregnancy: Blood RNAseq *before* pregnancy 🚺 improve during preg: Strong Neutrophil signature 🚺 experience dis worsening: Strong B cell signature Needs replication but could have major implications! @RheumNow #ACR23 ABST2481 https://t.co/gOHwEvOOM6