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      ACR#23 Abs #1023: IgG4-RD males > likely (vs females) to have multi-organ & serological activity w/ ^ immunoglobu

      Dr. Rachel Tate

      1 year ago
      ACR#23 Abs #1023: IgG4-RD males > likely (vs females) to have multi-organ & serological activity w/ ^ immunoglobulin concentrations. Interestingly, lower lipase levels observed in males are consistent with greater degrees of pancreatic damage. https://t.co/4hUGmzTQqX @rheumnow https://t.co/kcy5dL62Pn
      UTSW Dallas study: Health literacy may be essential limiting factor for families w/ children w/ SLE. Other critical barr

      Dr. Rachel Tate

      1 year ago
      UTSW Dallas study: Health literacy may be essential limiting factor for families w/ children w/ SLE. Other critical barriers to patient care include food security and living costs such as transportation, housing, and utilities. #ACR23 Abs #1029 https://t.co/jtnIgLZQfC @rheumnow https://t.co/A1zr8quSdd
      LV mass higher in pts with SLE nephritis.Nested case-control study 48 SLE pts +/- LN. LV mass higher w/LN (66.9 g/m2) v

      TheDaoIndex KDAO2011

      1 year ago
      LV mass higher in pts with SLE nephritis.Nested case-control study 48 SLE pts +/- LN. LV mass higher w/LN (66.9 g/m2) vs pts w/o LN (54.8 g/m2, p=0.035). Higher LV mass may increase risk for CV events as CHF, arrhythmias and CV mortality. @RheumNow #ACR23 abst#1447
      Real World SLE Rx patterns from the SPOCS cohort. 70+% IFN high, 81% on antimalarials, 21% biologics, and 55% IS, 65% GC

      TheDaoIndex KDAO2011

      1 year ago
      Real World SLE Rx patterns from the SPOCS cohort. 70+% IFN high, 81% on antimalarials, 21% biologics, and 55% IS, 65% GCs. High IFN pts had more IS and steroid use. 45+% still on GCs at 12 months despite avail of new therapeutics @RheumNow #ACR23 abst#0592
      Assessment of MAP kinase pathway gene expression prior to tx may aid in identification of polyarticular course JIA patie

      Dr. Rachel Tate

      1 year ago
      Assessment of MAP kinase pathway gene expression prior to tx may aid in identification of polyarticular course JIA patients that could exhibit poor response to tofacitinib. It may be helpful in personalized tx algorithm! #ACR23 Abs #0830 https://t.co/Z8pykbG7x5 @rheumnow https://t.co/ANZr8aVrVB
      STOP-JIA study data from Abs #0831 suggest improved effectiveness with early combination tx vs step up and biologic firs

      Dr. Rachel Tate

      1 year ago
      STOP-JIA study data from Abs #0831 suggest improved effectiveness with early combination tx vs step up and biologic first tx at the 2-3 yr timeframe for pJIA pts. More data needed to optimize outcomes/tx for these children. https://t.co/vWL5J4FPbo #ACR23 @rheumnow https://t.co/5iJpwglhPu
      Vasc Events in Danish Cohort: 3178 SLE pts matched to 60K controls. MI in SLE 2.9% vs 1.4%, cerebrovascular dz 7% vs 2.7

      TheDaoIndex KDAO2011

      1 year ago
      Vasc Events in Danish Cohort: 3178 SLE pts matched to 60K controls. MI in SLE 2.9% vs 1.4%, cerebrovascular dz 7% vs 2.7%, & PVD 5.5% vs 1.4%. IRR ranged 1.7-7.6. Female SLE pts had 3-5X risk for CVE, Male pts 6-8X risk. @RheumNow #ACR23 abst#1442 https://t.co/PapDiJ0shJ
      ACR 2023 is back in San Diego for its annual convergence of thousands of rheumatologists to partake, discover and learn from thousands of abstracts and hundreds of sessions and presentations. It was a big return for the Poster Hall with rows and rows of research, friends, fellows and poster tours.  Below are a few of my favorite presentations from the posters, Plenary and oral sessions on day one.
      Whether it’s RA, SLE or Sjogren’s, the increased prevalence of females affected by auto-immune diseases is well established, yet not fully understood. Often, I have heard that sexual hormones are responsible for every aspect of it. Two abstracts presented this year question this paradigm.
      The RheumNow faculty reporters have been scouring the meeting for what they believe to be the best presentations from the first day at ACR 2023 in San Diego.  From hundreds of online presentations, the poster floor and the plenary podium, here are some of the best abstracts from Sunday Nov. 12th. You can spot these on Twitter by looking for the (#ACRbest) hashtag.
      Obintuzumab in Lupus Nephritis

      Researchers found that treatment with obinutuzumab was superior to placebo for preservi

      Dr. John Cush RheumNow

      1 year ago
      Obintuzumab in Lupus Nephritis Researchers found that treatment with obinutuzumab was superior to placebo for preserving kidney function and preventing flares in patients with lupus nephritis. https://t.co/Sbh6k6XKjz https://t.co/aDbLUh7WtM
      Patient perspective: PP09 at #ACR23

      "Mindfulness helps me experience less suffering over pain" in patient with PsA + f

      Meral K. El Ramahi, MD MeralElRamahiMD

      1 year ago
      Patient perspective: PP09 at #ACR23 "Mindfulness helps me experience less suffering over pain" in patient with PsA + fibromyalgia. ⭐️Consider recommending mindfulness training such as mindfulness based stress reduction @RheumNow https://t.co/DHwduvTPZL
      ABS0122 at #ACR23

      ⭐️Risk of acute MI, stroke & death signif ⬆️ among RA/SLE pts w/ depress, anxiety, &amp

      Meral K. El Ramahi, MD MeralElRamahiMD

      1 year ago
      ABS0122 at #ACR23 ⭐️Risk of acute MI, stroke & death signif ⬆️ among RA/SLE pts w/ depress, anxiety, &/or PTSD vs w/o both RA/SLE ➡️U.S. pts: 3825 RA, 1862 SLE --> 1790 w/ above mental health dz, no prior CVD ➡️HR 1.28 after adjusting for🚬, obesity, & comorbidities @RheumNow https://t.co/sXMFtaKmYB
      ABS0155 @ #ACR23

      Economic impact of switching from SQ MTX (Rasuvo) from oral MTX in U.S. RA pts?'

      ➡️ Rasuvo assoc

      Meral K. El Ramahi, MD MeralElRamahiMD

      1 year ago
      ABS0155 @ #ACR23 Economic impact of switching from SQ MTX (Rasuvo) from oral MTX in U.S. RA pts?' ➡️ Rasuvo associated with significantly higher all cause total expenditure $4704 predominantly due to higher costs associated tin all cause pharmacy utilization $4,223! @Rheumnow https://t.co/ry8XxjvHRg