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Lupus

      Annals of Internal Medicine reports that thiopurine toxcicity risk is associated with the "CC" genotype and that azathioprine discontinuation was associated with hematopoietic toxicity and lower thiopurine doses. 
      Study of 1778 #SLE pts, of whom 121 had refractory thrombocytopenia (TP)(Plt <50K, unresp. to pred), Risk factors inc

      Dr. John Cush RheumNow

      3 years 2 months ago
      Study of 1778 #SLE pts, of whom 121 had refractory thrombocytopenia (TP)(Plt <50K, unresp. to pred), Risk factors included pregnancy, Autoimmune hemolytic anemia, decreased C3, severity of TP and elevated ACL-IgG. https://t.co/ZNqQfUoYUq https://t.co/eQNcKcc9Uz
      Watch: Dr. Lucy Carter on RNA-Seq analysis to determine who's at risk for SLE

      Dr. Yusof interviews Dr. Lucy Carter ( @L

      Dr. John Cush RheumNow

      3 years 3 months ago
      Watch: Dr. Lucy Carter on RNA-Seq analysis to determine who's at risk for SLE Dr. Yusof interviews Dr. Lucy Carter ( @LucyCarter6), winner of the #EULAR2022 Best Abstract Award for her work on ANA positivity in those at-risk for progression to #SLE. https://t.co/BdPnZRgwX4 https://t.co/g8xWWFthVC
      A retrospective cohort study has shown that outcomes in pregnant systemic lupus erythematosus (SLE) patients has significantly improved in the last decade, but there still is a high risk of adverse pregnancy outcomes (APO). A retrospective Danish SLE cohort was used to identify pregnancies in SLE patients from a single center between January 2010 and October 2020.
      Cluster study of 383 aPL+ pts showed 4 clusters:
      Cluster 1 (138): w/ SLE &amp; non-criteria Sxs
      Cluster 2 (112): pts w/

      Dr. John Cush RheumNow

      3 years 3 months ago
      Cluster study of 383 aPL+ pts showed 4 clusters: Cluster 1 (138): w/ SLE & non-criteria Sxs Cluster 2 (112): pts w/ CV risks Cluster 3 (83): females w/ OB morbidity (BEST outcome) Cluster 4 (50): lupus anticoagulant (+) (high freq of arterial thrombosis) https://t.co/HGRTceplsn https://t.co/ZDdwhCmj5r
      In SLE, two targets that are increasingly used are the DORIS 2021 Remission and the Lupus Low Disease Activity (LLDAS). T2T is more likely to be successful if the treating clinicians and the patients set the treatment goals together. What do our patients think about T2T and do they have any say/concern?
      Watch: EULAR 2022 - Day 1 Faculty Recap Pane

      Drs. Jack Cush, Eric Dein and Kathryn Dao discuss highlights from day 1 at

      Dr. John Cush RheumNow

      3 years 3 months ago
      Watch: EULAR 2022 - Day 1 Faculty Recap Pane Drs. Jack Cush, Eric Dein and Kathryn Dao discuss highlights from day 1 at #EULAR2022 - Guidelines, Lupus, and more. https://t.co/WSOCQ8K38p https://t.co/0u28QHtxoJ
      Watch this 4 minute video on Belimumab use in pregnancy featuring Dr. Kathryn Dao ( @KDAO2011 )

      https://t.co/8uRUIVURH

      Dr. John Cush RheumNow

      3 years 3 months ago
      Watch this 4 minute video on Belimumab use in pregnancy featuring Dr. Kathryn Dao ( @KDAO2011 ) https://t.co/8uRUIVURHF https://t.co/lbYwHFFJit
      RT @Yuz6Yusof: #LB0004 #EULAR2022 Positive Phase 2 results in #lupus! Deucravacitinib, a TYK2-inhibitor reported signifi

      Md Yuzaiful Md Yusof Yuz6Yusof

      3 years 3 months ago
      #LB0004 #EULAR2022 Positive Phase 2 results in #lupus! Deucravacitinib, a TYK2-inhibitor reported significantly more SRI-4 response rates in DEUC vs PBO. PBO: 34.4%; DEUC 3 mg BID:58.2%, DEUC 6 mg BID:49.5%, DEUC 12 mg QD:44.9%. No major safety. Will proceed to Phase 3 @RheumNow https://t.co/cZLv6bbHer
      Watch: Let’s Talk about Sex and Autoimmune Disease

      Dr. Eric Dein discusses abstract OP0139 presented at #EULAR2022.

      Dr. John Cush RheumNow

      3 years 3 months ago
      Watch: Let’s Talk about Sex and Autoimmune Disease Dr. Eric Dein discusses abstract OP0139 presented at #EULAR2022. https://t.co/fNcIbykFqL https://t.co/6UaH5DIc51
      RT @KDAO2011: My new blog on “Emerging Therapeutics for #Lupus” #EULAR22 @RheumNow. Tagging ⁦@RichardPAConway⁩ b

      TheDaoIndex KDAO2011

      3 years 3 months ago
      My new blog on “Emerging Therapeutics for #Lupus” #EULAR22 @RheumNow. Tagging ⁦@RichardPAConway⁩ because he doesn’t sleep. https://t.co/6a8Y00Aw4W
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