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      ALL-HEART study presented in Barcelona at ESC Congress 2022 showed that allopurinol given to 5,721 older adults without

      Dr. John Cush RheumNow

      3 years 2 months ago
      ALL-HEART study presented in Barcelona at ESC Congress 2022 showed that allopurinol given to 5,721 older adults without gout, failed to reduce # nonfatal myocardial infarction, nonfatal stroke or cardiovascular death in ischaemic heart Dz pts https://t.co/I0dFXQa6Ao https://t.co/8IevQ4uwUY
      Bidirectional Association Between Depression and Rheumatoid Arthritis

      A recent meta-analysis suggests a bidirectional

      Dr. John Cush RheumNow

      3 years 2 months ago
      Bidirectional Association Between Depression and Rheumatoid Arthritis A recent meta-analysis suggests a bidirectional association between RA and depression. Finding RA patients with depression yields an 80% increased mortality risk. https://t.co/NUyZ2jAWzE
      Weight Loss Slows Knee OA Progression

      Declines in body mass index (BMI) were linked with slower worsening of knee oste

      Dr. John Cush RheumNow

      3 years 2 months ago
      Weight Loss Slows Knee OA Progression Declines in body mass index (BMI) were linked with slower worsening of knee osteoarthritis (OA), according to data from three large longitudinal cohort studies. https://t.co/jJlSTdBdXT https://t.co/9mPJiVT9nE
      Axial Psoriatic Arthritis and Ankylosing Spondylitis with Psoriasis

      A cohort analysis from Toronto suggests that axial

      Dr. John Cush RheumNow

      3 years 2 months ago
      Axial Psoriatic Arthritis and Ankylosing Spondylitis with Psoriasis A cohort analysis from Toronto suggests that axial psoriatic arthritis (PsA) is distinctly different from axial ankylosing spondylitis (AS) with psoriasis. https://t.co/8bAoqp79Mg https://t.co/K2Z1LwPTiS
      Cochrane review of Stem cell transplantation in systemic sclerosis (3RCTs w/ 125 pts). Non‐myeloablative & myeloab

      Dr. John Cush RheumNow

      3 years 2 months ago

      Cochrane review of Stem cell transplantation in systemic sclerosis (3RCTs w/ 125 pts). Non‐myeloablative & myeloablative selective HSCT had moderate evidence for improved survival, skin thickness & function. But these had high Serious AE rates. https://t.co/VKciXY0klN https://t.co/LdMu3RrlZK

      RT @lupuscyclopedia: Learn how to manage lupus: 'The Lupus Encyclopedia: A Comprehensive Guide for Patients and Families

      Donald Thomas, MD lupuscyclopedia

      3 years 2 months ago
      Learn how to manage lupus: 'The Lupus Encyclopedia: A Comprehensive Guide for Patients and Families' - on #BookBuzz - https://t.co/hvnoFRiabA
      RT @LCalabreseDO: h/t @alhkim concluded. “Get Evusheld into your patients" - We add give aggressive out pt mgmnt for

      Leonard Calabrese LCalabreseDO

      3 years 2 months ago
      h/t @alhkim concluded. “Get Evusheld into your patients" - We add give aggressive out pt mgmnt for #Breakthrough @CCalabreseDO @philipcrobinson @drdavidliew B-cell depleting therapies ‘biggest threat’ for reduced SARS-CoV-2 mRNA vaccine response https://t.co/VZRwg0Q6cw
      Hyaluronic Acid Knee Injections Equivalent to Placebo

      In the United States, where over $300 million is spent annually o

      Dr. John Cush RheumNow

      3 years 2 months ago
      Hyaluronic Acid Knee Injections Equivalent to Placebo In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo. https://t.co/NwJkyECfgM https://t.co/qGLQMWjQG4
      Charcot (neuropathic) arthropathy of elbow due to Syringomyelia - review of 50 pts. Median age 45 yrs, 2/3 isolated elbo

      Dr. John Cush RheumNow

      3 years 2 months ago
      Charcot (neuropathic) arthropathy of elbow due to Syringomyelia - review of 50 pts. Median age 45 yrs, 2/3 isolated elbow arthritis; other joints: shoulder > wrist > MCPs/IPs. 2/3 had Chiari malformations, sensory/motor deficits, or ulnar neuropathy https://t.co/2hEArpbL8p https://t.co/MK4VTzSSRB
      Review of VTE risk with JAK inhibitors
      - Tofacitinib: 10mg or 5 mg bid - PE rates 0.5 & 0.3/100PY; higher w/ risk

      Dr. John Cush RheumNow

      3 years 2 months ago
      Review of VTE risk with JAK inhibitors - Tofacitinib: 10mg or 5 mg bid - PE rates 0.5 & 0.3/100PY; higher w/ risk factors, VTE 0.35/100PY - Baricitinib: IR of DVT/PE was 0.5/100PY - Filgotinib: 200mg VTEs 0.2/100PY Most VTE occured in LT extension of RCT https://t.co/xvf0kQUMel https://t.co/Bj6fmkktP7
      Dr. Jack Cush delivers this weeks rheumatology "weather report" with the best and least of news and journal articles fro

      Dr. John Cush RheumNow

      3 years 2 months ago
      Dr. Jack Cush delivers this weeks rheumatology "weather report" with the best and least of news and journal articles from the past week on RheumNow. Are you a fan of our podcast? Please rate, like and review us wherever you get your podcast. https://t.co/uj6QF3EqlU https://t.co/lFpoRfkEqU
      Melatonin Use Growing, Inappropriate & Potentially Unsafe

      With nearly 1/3 of adults, adolescents and children havi

      Dr. John Cush RheumNow

      3 years 2 months ago
      Melatonin Use Growing, Inappropriate & Potentially Unsafe With nearly 1/3 of adults, adolescents and children having sleep difficulties, many resort to using melatonin. But is it effective, safe and warranted? https://t.co/8TA76yAbwr https://t.co/ADYklo0yMz
      Olokizumab, another IL-6 Inhibitor for RA

      This week's NEJM has published the efficacy results of a large phase 3 trial

      Dr. John Cush RheumNow

      3 years 2 months ago
      Olokizumab, another IL-6 Inhibitor for RA This week's NEJM has published the efficacy results of a large phase 3 trial of olokizumab, a humanized monoclonal antibody that directly targets interleukin-6 (IL-6) in patients with rheumatoid arthritis (RA). https://t.co/VMz8xzffiZ https://t.co/eaA4CUWvrv
      Hyaluronic Acid Knee Injections Equivalent to Placebo

      In the United States, where over $300 million is spent annually o

      Dr. John Cush RheumNow

      3 years 2 months ago
      Hyaluronic Acid Knee Injections Equivalent to Placebo In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo. https://t.co/1pSVr3VI4t https://t.co/DvFN7WQdTp
      The CDC has published an update to the recommendations from the Advisory Committee on Immunization Practices (ACIP) on the use of seasonal influenza vaccines in the United States for the 2022-23 season.
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