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      The ACR is developing a new clinical practice guideline for systemic autoimmune rheumatic disease with interstitial lung

      Dr. John Cush RheumNow

      3 years 1 month ago
      The ACR is developing a new clinical practice guideline for systemic autoimmune rheumatic disease with interstitial lung disease (ILD). The Call for Public Comment is open until September 29, 2022. https://t.co/UxXDbGEQlh https://t.co/zGoBpbKLTC
      Forbes reports that a recent Merritt Hawkins survey shows that patients are waiting an average of 26 days for a scheduled appointment with a doctor. This is based on a 15 U.S. city survey of more than 1,000 physician offices - including family medicine, dermatology, obstetrics/gynecology, orthopedic surgery and cardiology practices. The average wait time is up 8% from 24.1 days in 2017 (It was 21 days in 2004).
      A longitudinal study of 506 ANCA-associated vasculitis (AAV) pts showed pts w/ negative ANCA serologies within 180 days

      Dr. John Cush RheumNow

      3 years 1 month ago
      A longitudinal study of 506 ANCA-associated vasculitis (AAV) pts showed pts w/ negative ANCA serologies within 180 days of induction had signif lower risk of relapse (HR 0.55; 0.38 to 0.81) but not for ESRD or death within 5 years. https://t.co/Dn8GGXnSDi https://t.co/C73hG9T7Au
      Deucravacitinib (Sotyktu), a first-in-class, oral, selective, allosteric tyrosine kinase 2 (TYK2) inhibitor, is the only approved TYK2 inhibitor worldwide and the first innovation in oral treatment for moderate-to-severe plaque psoriasis in nearly 10 years.
      Immunosuppresive (IST; MMF or AZA) withdrawl in 96 stable Lupus Nephritis pts also on HCQ. After 2 years, Relapse occurr

      Dr. John Cush RheumNow

      3 years 1 month ago
      Immunosuppresive (IST; MMF or AZA) withdrawl in 96 stable Lupus Nephritis pts also on HCQ. After 2 years, Relapse occurred in 12.5% w/ IST continued & 27.3% with IST D/C (Not noninferior). Less Severe SLE flares (renal & extrarenal) w/ IST continuation https://t.co/XWmJpkqhG9 https://t.co/gYM24QIiYz
      COVID Outcomes in Dermatomyositis

      A retrospective study of dermatomyositis (DM) patients with COVID-19, shows that DM

      Dr. John Cush RheumNow

      3 years 1 month ago
      COVID Outcomes in Dermatomyositis A retrospective study of dermatomyositis (DM) patients with COVID-19, shows that DM patients without comorbidities fair well (with regard to mortality and hospitalisation). https://t.co/nlCVHt3XeS https://t.co/Bhc47k7rMD
      Does Fibromyalgia Need B12?

      Can we predict the bad outcomes? Like when ITP evolves into SLE; or when psoriasis will dev

      Dr. John Cush RheumNow

      3 years 1 month ago
      Does Fibromyalgia Need B12? Can we predict the bad outcomes? Like when ITP evolves into SLE; or when psoriasis will develop arthritis; or if Sjogren's will develop lymphoma? Let's dive in and review these journal reports and this past week's news. https://t.co/ztDVHfGegM https://t.co/ux4F0UIIld
      Spanish SpA Registry (REGISPONSER) - 18.3% had psoriasis; w/ 3/4 of these (76%) having PSO before MSK Sxs. Pts w/ PSO be

      Dr. John Cush RheumNow

      3 years 1 month ago
      Spanish SpA Registry (REGISPONSER) - 18.3% had psoriasis; w/ 3/4 of these (76%) having PSO before MSK Sxs. Pts w/ PSO before MSK Sxs had shorter dz duration, lower BMI, Less B27 & anterior uveitis, more dactylitis and ^risk PsA dx (78% vs 56%) https://t.co/xchK5ETmg3 https://t.co/F9klsUE5er
      Study of 130 patients with ITP (w/ 10 later Dx SLE (30 mos F/U). Risk factors for ITP developing SLE included young age

      Dr. John Cush RheumNow

      3 years 1 month ago
      Study of 130 patients with ITP (w/ 10 later Dx SLE (30 mos F/U). Risk factors for ITP developing SLE included young age (< 40yrs; OR 6.3), organ bleeding (OR 13.7), and ANA (≥ 1:160; OR 6.6) https://t.co/o9sO5WQmcq https://t.co/6RrrKzu41p
      Voclosporin Efficacy and Safety in Lupus Nephritis

      An integrated analysis of two pivotal trials of voclosporin, a calci

      Dr. John Cush RheumNow

      3 years 1 month ago
      Voclosporin Efficacy and Safety in Lupus Nephritis An integrated analysis of two pivotal trials of voclosporin, a calcineurin inhibitor, in lupus nephritis patients saw significant improvement in complete renal responses (CRR) at one year. https://t.co/WqQ7wdzmCc https://t.co/uxFb6Nbdgi
      Multicentre matched control study looked at primary Sjogrens that developed lymphoma or NOT. Parotid swelling (PSW) is a

      Dr. John Cush RheumNow

      3 years 1 month ago
      Multicentre matched control study looked at primary Sjogrens that developed lymphoma or NOT. Parotid swelling (PSW) is an early major predictor of non-Hodgkin lymphoma in pSS; esp if present before or dx, & w/ a longer duration of PSW https://t.co/wCyZjRbWe8 https://t.co/U0LlDnuNtZ
      B12 or Placebo effect? Open label study of B12 (1000mcg/d) in 29 fibromyalgia pts showed after 50d, significant reductio

      Dr. John Cush RheumNow

      3 years 1 month ago
      B12 or Placebo effect? Open label study of B12 (1000mcg/d) in 29 fibromyalgia pts showed after 50d, significant reductions in FM Impact Quest. (FIQR; 49.8 to 40.00; p< 0.01), Function, Sxs, anxiety scores all signif improved. https://t.co/OEJ4RY2EkY https://t.co/afkcIHMYVz
      FDA has approvef deucravacitinib (Sotyktu), an oral TYK2 inhibitor, for use in adults with Moderate-to-Severe Plaque Pso

      Dr. John Cush RheumNow

      3 years 1 month ago
      FDA has approvef deucravacitinib (Sotyktu), an oral TYK2 inhibitor, for use in adults with Moderate-to-Severe Plaque Psoriasis. Approval was based on pivotal Phase 3 POETYK PSO clinical trials demonstrated superior efficacy over PBO & apremilast https://t.co/mkRgVZ0Crh https://t.co/833jGV1yO4
      FDA has approved SPEVIGO® (spesolimab-sbzo) an IV injection - the first-approved treatment option for generalized pustu

      Dr. John Cush RheumNow

      3 years 1 month ago
      FDA has approved SPEVIGO® (spesolimab-sbzo) an IV injection - the first-approved treatment option for generalized pustular psoriasis (GPP) FLARES. Spesolimab is an interleukin-36 receptor antagonist. https://t.co/zmuB1tyw9W https://t.co/bJiQB5qJNl
      Does Fibromyalgia Need B12?

      Can we predict the bad outcomes? Like when ITP evolves into SLE; or when psoriasis will dev

      Dr. John Cush RheumNow

      3 years 1 month ago
      Does Fibromyalgia Need B12? Can we predict the bad outcomes? Like when ITP evolves into SLE; or when psoriasis will develop arthritis; or if Sjogren's will develop lymphoma? Let's dive in and review these journal reports and this past week's news. https://t.co/NmAQkuBxg1 https://t.co/W89EImXlvE
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