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      StillsNow Podcast August 2022 - Genetic Testing for Autoinflammatory Diseases

      Featuring a discussion with Dr. Susan Sh

      Dr. John Cush RheumNow

      3 years 1 month ago
      StillsNow Podcast August 2022 - Genetic Testing for Autoinflammatory Diseases Featuring a discussion with Dr. Susan Shenoi from Seattle Childrens Hospital https://t.co/W9e6r83R6B https://t.co/rVvDurZz2g
      Voclosporin Efficacy and Safety in Lupus Nephritis

      An integrated analysis of two pivotal trials of voclosporin, a calci

      Dr. John Cush RheumNow

      3 years 1 month ago
      Voclosporin Efficacy and Safety in Lupus Nephritis An integrated analysis of two pivotal trials of voclosporin, a calcineurin inhibitor, in lupus nephritis patients saw significant improvement in complete renal responses (CRR) at one year. https://t.co/LSjmRB2Zr3 https://t.co/z9MoJ0uRzz
      Finkh et al report on the prevalence and interesting trends in rheumatoid arthritis (RA), including its higher prevalence in industrialized countries and declining disease severity over time. 
      Study of 100 Korean systemic sclerosis pts, shows that while many had SSc finger involvement, fingerprints is SSc pts d

      Dr. John Cush RheumNow

      3 years 1 month ago
      Study of 100 Korean systemic sclerosis pts, shows that while many had SSc finger involvement, fingerprints is SSc pts did not change significantly, but may be inadequate/ difficulr with finger deformity, acroosteolysis or digital ulcers https://t.co/JjTIiaLYZv https://t.co/kcFUobVnvi
      ACR RISE Registry, 9,560 gout pts- ONLY 56% of patients had > = one Serum Urate recorded during the year; amongst tho

      Dr. John Cush RheumNow

      3 years 1 month ago
      ACR RISE Registry, 9,560 gout pts- ONLY 56% of patients had > = one Serum Urate recorded during the year; amongst those w/ 1 SU recorded, 74% achieved the SU target. ONLY HALF? GETTING SUAs? Are we not Rheums? https://t.co/OfKRWtyjBT https://t.co/8kjwEVZwB3
      Multicentre matched control study looked at primary Sjogrens that developed lymphoma or NOT. Parotid swelling (PSW) is a

      Dr. John Cush RheumNow

      3 years 1 month ago
      Multicentre matched control study looked at primary Sjogrens that developed lymphoma or NOT. Parotid swelling (PSW) is an early major predictor of non-Hodgkin lymphoma in pSS; esp if present before or dx, & w/ a longer duration of PSW https://t.co/QokXF6klEv https://t.co/YqFgAqt4ku
      Hypertension Associated with RA and OA

      Analysis of NHANES data suggests that both rheumatoid arthritis (RA) and osteoa

      Dr. John Cush RheumNow

      3 years 1 month ago
      Hypertension Associated with RA and OA Analysis of NHANES data suggests that both rheumatoid arthritis (RA) and osteoarthritis (OA) are strongly associated with hypertension (HTN). https://t.co/HUWUvOKcMw https://t.co/6GkeEWQP40
      Among U.S. veterans receiving hydroxychloroquine (HCQ) as long-term therapy for rheumatoid arthritis, development of long QT syndrome was rare and not markedly more common compared with similar patients treated with other agents, researchers said.
      Genetic Testing for Autoinflammatory Disease

      Not all patients with periodic fevers fit neatly into diagnostic categori

      Dr. John Cush RheumNow

      3 years 1 month ago
      Genetic Testing for Autoinflammatory Disease Not all patients with periodic fevers fit neatly into diagnostic categories. Some can be diagnosed as Still’s disease (based on criteria) while others can be classified as AID and some may be unclassifiable. https://t.co/E5qZS1JyAY https://t.co/PYgUbiduPF
      Nintedinib has been studied in 39 children (6–17 yrs) with fibrosing ILD demonstrating pharmacokinetics (wt based dosi

      Dr. John Cush RheumNow

      3 years 1 month ago
      Nintedinib has been studied in 39 children (6–17 yrs) with fibrosing ILD demonstrating pharmacokinetics (wt based dosing) and safety. Adjusted mean changes in FVC % at week 24 were 0.3 with nintedanib and −0.9 with placebo https://t.co/yQ7OREzpTR https://t.co/iylG9BZiz4
      An integrated analysis of two pivotal trials of voclosporin, a calcineurin inhibitor, in lupus nephritis patients saw significant improvement in complete renal responses (CRR) at one year.
      B12 or Placebo effect? Open label study of B12 (1000mcg/d) in 29 fibromyalgia pts showed after 50d, significant reductio

      Dr. John Cush RheumNow

      3 years 1 month ago
      B12 or Placebo effect? Open label study of B12 (1000mcg/d) in 29 fibromyalgia pts showed after 50d, significant reductions in FM Impact Quest. (FIQR; 49.8 to 40.00; p< 0.01), Function, Sxs, anxiety scores all signif improved. https://t.co/MtJWy5xlz9 https://t.co/kzvA1wd3zb
      FDA has approved SPEVIGO® (spesolimab-sbzo) an IV injection - the first-approved treatment option for generalized pustu

      Dr. John Cush RheumNow

      3 years 1 month ago
      FDA has approved SPEVIGO® (spesolimab-sbzo) an IV injection - the first-approved treatment option for generalized pustular psoriasis (GPP) FLARES. Spesolimab is an interleukin-36 receptor antagonist. https://t.co/izmExVCvfQ https://t.co/FELKR70UMv
      Dr. Jack Cush discusses declining survival rates in the USA, FDA approvals of new COVID subvariant boosters and other od

      Dr. John Cush RheumNow

      3 years 1 month ago
      Dr. Jack Cush discusses declining survival rates in the USA, FDA approvals of new COVID subvariant boosters and other odd and possibly true new research reports from the past week on RheumNow. https://t.co/JqzZRu2HYR https://t.co/XefaHown4g https://t.co/XiMyDLhKIe
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