Aurelie Najm AurelieRheumo
2 years 5 months ago
Insightful session with H Schulze-Koops: JAKi-Are all promises fulfilled?
"JAKi have not shown us sufficient data to prove that they can induce remission or inhibit disease progression"
@RheumNow #EULAR2022 https://t.co/SKKAS1ViIU
TheDaoIndex KDAO2011
2 years 5 months ago
Dr. Werth shared her evidence based algorithm for managing cutaneous lupus published here: https://t.co/RytrxLdLHK #EULAR2022 @rheumnow https://t.co/wq28btM24U
Eric Dein ericdeinmd
2 years 5 months ago
#EULAR2022 @ChristianDejaco: Do we need see our patient at all?
Provocative statement asking if some disease states can be evaluated, diagnosed, educated and monitored digitally.
"It's already out there!" "Should we leave it to the market" or should rheum take a lead?
@RheumNow https://t.co/iMrlKZgtbg
Richard Conway RichardPAConway
2 years 5 months ago
Casado et al. Efficacy of US guided needle fragmentation or lavage for calcific tendonitis refractory subacromial injection. Mean VAS decreased from 7.6±1.5 to 4.5±3.8 at month 4, 82.9% radiologic improvement. No control group! @RheumNow #EULAR2022 OP0289 https://t.co/KarkB7XL8u
Robert B Chao, MD doctorRBC
2 years 5 months ago
Pregnancy data in SpA from 122 pts
40% flared during pregnancy, more frequent 2nd trimester, pts w/ axial dz
7 pts required start of TNFi during 2nd or 3rd trimester
40% post-partum
@RheumNow #EULAR2022 ABST#POST0151 https://t.co/cdFRhRuCVH
Eric Dein ericdeinmd
2 years 5 months ago
#EULAR2022 POS0276
Xray & US for CPPD:
US: sensitivity in all sites
Xray: highly specific, low sensitivity
Combo: Best for patients with Negative Xray or Inconclusive US (only one positive site)
@Rheumnow @MymaAlbaydaMD @USSONAR_Rh
David Liew drdavidliew
2 years 5 months ago
PMR/GCA patients: should you be worried about how well your COVID vaccine worked?
Actually, post-two vaccines, pretty good Ab (&cellular) response, esp if not on MTX/PNL>10
Glad to see our PMR/GCA pts protected
@VasculitisUMCG @SleenYannick @ElisabethBrouw3 #EULAR2022 @RheumNow https://t.co/9vy0W4ojOF
Richard Conway RichardPAConway
2 years 5 months ago
Boers et al. GLORIA trial of long term 5mg pred in RA. Titled as "favourable balance of benefit and harm". I cannot agree. 24% increase adverse events, NNH 9, for DAS28 0.37 better at 1 year, and really no difference after that. @RheumNow #EULAR2022 OP0263 https://t.co/eO4f1CjH5q https://t.co/VyyZm1QvYy
Richard Conway RichardPAConway
2 years 5 months ago
Meudec et al. Comparative effects of JAKi on NK cell function on cancer cells (lymphoma and lung cancer). Tofacitinib had most negative impact. Interesting given blanket black box based on tofa data! @RheumNow #EULAR2022 OP0265 https://t.co/XSE7hP60Ui https://t.co/MjtAJcvWAD
Robert B Chao, MD doctorRBC
2 years 5 months ago
Deep learning can be used to distinguish seropositive RA from seronegative RA and PsA based on MRI.
Early changes in PsO may suggest a PsA-like MRI pattern may be present!
Is this how we predict which PsO -> PsA?
@RheumNow #EULAR2022 ABST#OP0292 https://t.co/NGfFkSqlaM
Richard Conway RichardPAConway
2 years 5 months ago
Nyam et al. JAK-pot study. >90000 treatment courses. No difference in aHR for treatment stop due to adverse events in JAKi vs TNFi or non-TNF bDMARD. @RheumNow #EULAR2022 OP0266 https://t.co/3tgADvH1Bq https://t.co/2qLRzfMB9c
Richard Conway RichardPAConway
2 years 5 months ago
Zabotti et al. IL23i guselkumab. Machine learning identified clusters of MDA response @RheumNow #EULAR2022 OP0259 https://t.co/67tfuADxLs https://t.co/33Y5m37K3y
Eric Dein ericdeinmd
2 years 5 months ago
#EULAR2022 POS0278:
Proof of concept US study:
💎CPP crystals do NOT generate posterior shadowing
💎MSU and hydroxyapatite did have shadowing, proportional to concentration of crystals
@Rheumnow @MymaAlbaydaMD @USSONAR_Rh
David Liew drdavidliew
2 years 5 months ago
There's nothing like a good physical examination
Temporal artery exam & ultrasound vs temporal artery biopsy
n=97 consecutive ?GCA pts from Carlo Salvarini's group
Very decent PPV
Those TA exam findings can be hard to find, but they're gold dust.
POS0820 #EULAR2022 @RheumNow https://t.co/X9TzIqQBaB
Eric Dein ericdeinmd
2 years 5 months ago
#EULAR2022 POS0213
Beware of paradoxical low lipids in RA!
⭐️ETN+MTX vs MTX T2T:
Early ETN: increased in HLD, lesser LDL, differs from MTX. Correlates with clinical disease activity
@RheumNow https://t.co/c6GXadVwYN